Identification of potential antigenic peptides of Brucella through proteome and peptidome
Based on proteomics and peptidomics, we identified 35 peptides from the Brucella proteome, which have the ability to bind MHC molecules and have the potential to be used in vaccine design. In addition, we also found four Brucella proteins containing the identified MHC‐I and MHC‐II binding peptides, which may be good candidate targets for designing ...
Meijuan Pei+10 more
wiley +1 more source
Non‐cytopathic bovine viral diarrhoea virus 2 induces autophagy to enhance its replication
Ncp BVDV2 infection induced autophagy in MDBK cells via anti‐apoptosis and PKR suppression. Autophagy may play a role in establishing persistent infection caused by ncp BVDV. Abstract Background Bovine viral diarrhoea virus (BVDV) is an important viral pathogen that has an economic impact on the livestock industry worldwide.
Seung‐Uk Shin+4 more
wiley +1 more source
THE CHANGING CLINICAL PERFORMANCE OF DENGUE VIRUS INFECTION IN THE YEAR 2009
Background: Dengue (DEN) virus, the most important arthropod-borne human pathogen, represents a serious public health threat. DEN virus is transmitted to humans by the bite of the domestic mosquito, Aedes aegypti, and circulates in nature as four ...
Soegeng Soegijanto+4 more
doaj +1 more source
A little less aggregation a little more replication: Viral manipulation of stress granules
Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley +1 more source
FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
Dengue Virus Infections are distributed in tropical and sub-tropical regions and transmitted by the mosquitoes such as Aedes aegypti and Aedes albopictus.
Soegeng Soegijanto+3 more
doaj +1 more source
Zika virus (ZIKV) was discovered in 1947 and was thought to lead to relatively mild disease. The recent explosive outbreak of ZIKV in South America has led to widespread concern, with reports of neurological sequelae ranging from Guillain Barré syndrome ...
W. Dejnirattisai+11 more
semanticscholar +1 more source
DEMAM BERDARAH DENGUE (DBD) DAN NS1 ANTIGEN UNTUK DETEKSI DINI INFEKSI AKUT VIRUS DENGUE
Demam Berdarah Dengue (DBD) atau Dengue Hemorrhagic Fever (DHF) disebabkan oleh infeksi virus dengue. Virus dengue merupakan virus RNA yang termasuk ke dalam famili flaviviridae , genus flavivirus dan ada 4 serotipe yang berbeda yaitu DEN1, DEN 2, DEN ...
Meddy Setiawan
doaj +1 more source
Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando+11 more
core +2 more sources
Vitamin D—A prominent immunomodulator to prevent COVID‐19 infection
Abstract COVID‐19 remains a life‐threatening infectious disease worldwide. Several bio‐active agents have been tested and evaluated in an effort to contain this disease. Unfortunately, none of the therapies have been successful, owing to their safety concerns and the presence of various adverse effects.
Sumel Ashique+13 more
wiley +1 more source
Zika Virus Mutation and The Spreading to Indonesia [PDF]
More than 13 countries in the Americas have reported sporadic Zika virus infection that show very rapid geographic expansion. While in Indonesia, the euphoria is also increasingly prevalent virus discussed especially after the discovery of Jambi positive
Amiroch, Siti, Pradana, Mohammad Syaiful
core +2 more sources