RNA sensors enable human mast cell anti-viral chemokine production and IFN-mediated protection in response to antibody-enhanced dengue virus infection. [PDF]
PLoS ONE, 2012 Dengue hemorrhagic fever and/or dengue shock syndrome represent the most serious pathophysiological manifestations of human dengue virus infection.
Michael G Brown +6 more
doaj +1 more source
The Epidemiology, Virology and Clinical Findings of Dengue Virus Infections in a Cohort of Indonesian Adults in Western Java. [PDF]
PLoS Neglected Tropical Diseases, 2016 Dengue has emerged as one of the most important infectious diseases in the last five decades. Evidence indicates the expansion of dengue virus endemic areas and consequently the exponential increase of dengue virus infections across the subtropics.
Herman Kosasih +15 more
doaj +1 more source
Models of dengue virus infection [PDF]
Drug Discovery Today: Disease Models, 2006 The need for models of dengue disease has reached a pinnacle as the transmission of this mosquito-borne virus has increased dramatically. Little is known about the mechanisms that lead to dengue fever and its more severe form, dengue hemorrhagic fever; this is owing to the fact that only humans show signs of disease.
Rebeca Rico-Hesse, Dennis A. Bente
openaire +3 more sources
Identification of potential antigenic peptides of Brucella through proteome and peptidome
Veterinary Medicine and Science, Volume 9, Issue 1, Page 523-534, January 2023., 2023 Based on proteomics and peptidomics, we identified 35 peptides from the Brucella proteome, which have the ability to bind MHC molecules and have the potential to be used in vaccine design. In addition, we also found four Brucella proteins containing the identified MHC‐I and MHC‐II binding peptides, which may be good candidate targets for designing ...
Meijuan Pei +10 more
wiley +1 more source
Lipidated dengue-2 envelope protein domain III independently stimulates long-lasting neutralizing antibodies and reduces the risk of antibody-dependent enhancement. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND: Dengue virus is a mosquito-transmitted virus that can cause self-limiting dengue fever, severe life-threatening dengue hemorrhagic fever and dengue shock syndrome.
Chen-Yi Chiang +9 more
doaj +1 more source
Spatial and temporal clustering of dengue virus transmission in Thai villages. [PDF]
, 2008 BackgroundTransmission of dengue viruses (DENV), the leading cause of arboviral disease worldwide, is known to vary through time and space, likely owing to a combination of factors related to the human host, virus, mosquito vector, and environment.
Aldstadt, Jared +15 more
core +3 more sources
The reemergence of dengue virus in Sudan
Journal of Infection and Public Health, 2023 Dengue fever (DF) is a mosquito-transmitted arboviral disease caused by 1 of 4 closely related but antigenically distinct serotypes of dengue virus (DENV), DENV-1-4. The primary vector of DENV is Aedes aegypti and Aedes albopictus mosquitoes. Humans are the main carrier of the virus and the amplifying host with non-human primates plays a considerable ...
Mujahed I. Mustafa +1 more
openaire +3 more sources
Non‐cytopathic bovine viral diarrhoea virus 2 induces autophagy to enhance its replication
Veterinary Medicine and Science, Volume 9, Issue 1, Page 405-416, January 2023., 2023 Ncp BVDV2 infection induced autophagy in MDBK cells via anti‐apoptosis and PKR suppression. Autophagy may play a role in establishing persistent infection caused by ncp BVDV. Abstract Background Bovine viral diarrhoea virus (BVDV) is an important viral pathogen that has an economic impact on the livestock industry worldwide.
Seung‐Uk Shin +4 more
wiley +1 more source
The Role Activity of Complement, TNFα & IL12 in Pathogenesis Dengue Virus
Indonesian Journal of Tropical and Infectious Disease, 2010 Dengue Virus infection is always found in some part of the world especially South East Asia including Indonesia. The pathogenesis of Dengue Virus infection is still controversial.
Soegeng Soegijanto +3 more
doaj +1 more source
A little less aggregation a little more replication: Viral manipulation of stress granules
WIREs RNA, Volume 14, Issue 1, January/February 2023., 2023 Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley +1 more source