Central nervous system involvement of dengue virus is increasingly reported from endemic areas. This study describes the clinical characteristics and laboratory features of a pediatric patient enrolled in a central nervous system illness study conducted ...
Dewi Hawani Alisjahbana+10 more
doaj +1 more source
Intrahost Selection Pressures Drive Rapid Dengue Virus Microevolution in Acute Human Infections. [PDF]
Dengue, caused by four dengue virus serotypes (DENV-1 to DENV-4), is a highly prevalent mosquito-borne viral disease in humans. Yet, selection pressures driving DENV microevolution within human hosts (intrahost) remain unknown. We employed a whole-genome
Balmaseda, Angel+6 more
core +1 more source
Dengue is of great concern in various parts of the world, especially in tropical and subtropical countries where the mosquito vectors Aedes aegypti and Aedes albopictus are present. The transmission of this virus to humans, by what is known as horizontal
Victor Henrique Ferreira-de-Lima+1 more
semanticscholar +1 more source
An intact signal peptide on dengue virus E protein enhances immunogenicity for CD8+ T cells and antibody when expressed from modified vaccinia Ankara [PDF]
Dengue is a global public health concern and this is aggravated by a lack of vaccines or antiviral therapies. Despite the well-known role of CD8(+) T cells in the immunopathogenesis of Dengue virus (DENV), only recent studies have highlighted the ...
Coelho, Fabiana M.+5 more
core +1 more source
The Epidemiology, Virology and Clinical Findings of Dengue Virus Infections in a Cohort of Indonesian Adults in Western Java. [PDF]
Dengue has emerged as one of the most important infectious diseases in the last five decades. Evidence indicates the expansion of dengue virus endemic areas and consequently the exponential increase of dengue virus infections across the subtropics.
Herman Kosasih+15 more
doaj +1 more source
Pemeriksaan Virus Dengue-3 Pada Nyamuk Aedes Aegypti Yang Diinfeksi Secara Intrathorakal Dengan Teknik Imunositokimia Menggunakan Antibodi Dsse10 [PDF]
Dengue viruses, globally the most prevalent arboviruses, are transmitted to humans by persistently infectedAedes mosquitoes. The most important vector of Dengue virus is the mosquito Ae.aegypti, which should be the main targetof surveillance and control ...
Umniyati, S. R. (Sitti)+2 more
core +3 more sources
Dengue virus and the host innate immune response
Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There are four serotypes of the virus.
Naoko Uno, T. Ross
semanticscholar +1 more source
Models of dengue virus infection [PDF]
The need for models of dengue disease has reached a pinnacle as the transmission of this mosquito-borne virus has increased dramatically. Little is known about the mechanisms that lead to dengue fever and its more severe form, dengue hemorrhagic fever; this is owing to the fact that only humans show signs of disease.
Rebeca Rico-Hesse, Dennis A. Bente
openaire +3 more sources
Lipidated dengue-2 envelope protein domain III independently stimulates long-lasting neutralizing antibodies and reduces the risk of antibody-dependent enhancement. [PDF]
BACKGROUND: Dengue virus is a mosquito-transmitted virus that can cause self-limiting dengue fever, severe life-threatening dengue hemorrhagic fever and dengue shock syndrome.
Chen-Yi Chiang+9 more
doaj +1 more source
The possible role of cross-reactive dengue virus antibodies in Zika virus pathogenesis
Zika virus (ZIKV) has been known for decades to circulate in Africa and Asia. However, major complications of a ZIKV infection have recently become apparent for reasons that are still not fully elucidated.
T. Langerak+6 more
semanticscholar +1 more source