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In this chapter, we will draw attention to the possibility of viral encephalitis caused by a common pathogen: dengue. To this end, it includes necessary knowledge of diagnosis and therapeutic management, such as general notions of infections in the central nervous system; viral encephalitis—diagnostic and therapeutic investigation; arboviruses and ...
Novaes, Botelho, Wesley Gabriel+3 more
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Pathogenic viruses have RNA genomes that cause acute and chronic infections. These viruses replicate with high mutation rates and exhibit significant genetic diversity, so-called viral quasispecies. Viral quasispecies play an important role in chronic infectious diseases, but little is known about their involvement in acute infectious diseases such as ...
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Zika virus: New clinical syndromes and its emergence in the western hemisphere [PDF]
Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern.
Brazilian Medical Genetics Society–Zika Embryopathy Task Force+9 more
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Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each ...
Acosta, Eliana Gisela+2 more
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Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop [PDF]
Detection of antibodies is widely used for the diagnosis of infections with arthropod-borne flaviviruses including dengue (DENV) and Zika virus (ZIKV). Due to the emergence of ZIKV in areas endemic for DENV, massive co-circulation is observed and methods
Barzon, Luisa+12 more
core +2 more sources
The complex relationship between weather and dengue virus transmission in Thailand. [PDF]
Using a novel analytical approach, weather dynamics and seasonal dengue virus transmission cycles were profiled for each Thailand province, 1983-2001, using monthly assessments of cases, temperature, humidity, and rainfall.
Campbell, Karen M+3 more
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Prospects for a dengue virus vaccine [PDF]
The number of cases of severe dengue disease continues to grow in endemic areas of southeast Asia, Central and South America, and other subtropical regions. Children bear the greatest burden of disease, and the development of an effective vaccine remains a global public health priority.
Brian R. Murphy+3 more
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Photoelectrochemical Detection of Dengue-Related Oligonucleotide Sequence Using Anthocyanin as an Intercalating Agent and Electrochromic Material [PDF]
World Health Organization (WHO) presupposes a confirmation of dengue virus infection diagnosis with two criteria, i.e. clinical and laboratory criteria.
Ibrahim, A. S. (Anwar)+2 more
core
A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis [PDF]
The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium.
Diamond, Michael S+4 more
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Zika virus and the never-ending story of emerging pathogens and transfusion medicine [PDF]
In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses.
Grazzini, Giuliano+4 more
core +1 more source