Results 41 to 50 of about 100,685 (253)
Background: Dengue is a rapidly emerging arthropod borne viral infection affecting tropical and sub-tropical regions of the world. Dengue is an acute febrile illness but sometimes causes more fatal complications like dengue haemorrhagic fever (DHF) and ...
Nazish Parveen +9 more
doaj +1 more source
Increased PAI-1 plasma levels and risk of death from dengue: no association with the 4G/5G promoter polymorphism [PDF]
Background: Dengue virus infected patients have high plasminogen activator inhibitor type I (PAI-1) plasma concentrations. Whether the insertion/deletion (4G/5G) polymorphism in the promotor region of the PAI-1 gene is associated with increased PAI-1 ...
ten Cate, H +78 more
core +1 more source
Development of MVA-d34 Tetravalent Dengue Vaccine: Design and Immunogenicity
Dengue fever, an infectious disease that affects more than 100 million people every year, is a global health problem. Vaccination may be the most effective prevention strategy for the disease.
Ramil R. Mintaev +6 more
doaj +1 more source
Corticosteroids for dengue - why don't they work? [PDF]
BACKGROUND: Dysregulated immune responses may contribute to the clinical complications that occur in some patients with dengue. FINDINGS: In Vietnamese pediatric dengue cases randomized to early prednisolone therapy, 81 gene-transcripts (0.2% of the 47 ...
Tuan Trung Vu +61 more
core +1 more source
Rapid Detection and Molecular Typing of Dengue Virus by Using Multiplex-Nested-RT-PCR
world. We have evaluated the combination of one-step RT-PCR and multiplex nested PCR assays for detecting dengue viruses from clinical samples. Twelve patients were screened for the dengue virus, using a pair of primers that conserve for several ...
Nastiti Wijayanti +4 more
doaj +1 more source
In the past decade, dengue virus infection is one of the most prevalent and rapidly spreading arthropod-borne diseases worldwide with about 400 million infections every year.
Yaoxing Wu +7 more
doaj +1 more source
The early clinical features of dengue in adults: challenges for early clinical diagnosis. [PDF]
BACKGROUND: The emergence of dengue throughout the tropical world is affecting an increasing proportion of adult cases. The clinical features of dengue in different age groups have not been well examined, especially in the context of early clinical ...
Chaterji, S. +67 more
core +1 more source
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
The monocyte-macrophage-mast cell axis in dengue pathogenesis
Dengue virus, the causative agent of dengue disease which may have hemorrhagic complications, poses a global health threat. Among the numerous target cells for dengue virus in humans are monocytes, macrophages and mast cells which are important ...
Shu-Wen Wan +5 more
doaj +1 more source
Polytope Prediction for Dengue Vaccine Candidate Based on Conserved Envelope Glycoprotein of Four Serotypes of Dengue Virus and Its Antigenicity [PDF]
Dengue fever reported endemic in tropical and sub-tropical country. Dengue fever caused by dengue virus, has Envelope protein that often used for vaccine development to prevent the virus infection.
Karimatul Himmah +4 more
doaj +1 more source

