Results 31 to 40 of about 100,685 (253)

The Epidemiology, Virology and Clinical Findings of Dengue Virus Infections in a Cohort of Indonesian Adults in Western Java. [PDF]

PLoS Neglected Tropical Diseases, 2016
Dengue has emerged as one of the most important infectious diseases in the last five decades. Evidence indicates the expansion of dengue virus endemic areas and consequently the exponential increase of dengue virus infections across the subtropics.
Herman Kosasih, Bachti Alisjahbana, Nurhayati, Quirijn de Mast, Irani F Rudiman, Susana Widjaja, Ungke Antonjaya, Harli Novriani, Nugroho H Susanto, Hadi Jusuf, Andre van der Ven, Charmagne G Beckett, Patrick J Blair, Timothy H Burgess, Maya Williams, Kevin R Porter   +15 more
doaj   +1 more source

Estimates of dengue force of infection in children in Colombo, Sri Lanka. [PDF]

, 2013
Dengue is the most important vector-borne viral disease worldwide and a major cause of childhood fever burden in Sri Lanka, which has experienced a number of large epidemics in the past decade.
Harold S Margolis, Margolis H.S., Aruna Dharshan De Silva (350174), Tam, Clarence C., Amarasinge, Ananda, Margolis, Harold S., de Silva A.D., de Silva, Aravinda M, Clarence C Tam, Harold S. Margolis (147272), Tissera, Hasitha, Aruna Dharshan De Silva, Aravinda M. de Silva (180486), de Silva, Aravinda M., Clarence C. Tam (378980), Hasitha Tissera (419200), Tam, Clarence C, Ananda Amarasinge (419201), Aravinda M de Silva, Tissera H., de Silva A.M., Amarasinge A., De Silva, Aruna Dharshan, Tam C.C., Hasitha Tissera, Ananda Amarasinge, Margolis, Harold S   +26 more
core   +1 more source

The Role Activity of Complement, TNFα & IL12 in Pathogenesis Dengue Virus

Indonesian Journal of Tropical and Infectious Disease, 2010
Dengue Virus infection is always found in some part of the world especially South East Asia including Indonesia. The pathogenesis of Dengue Virus infection is still controversial.
Soegeng Soegijanto, Dian Dwi Sary, Budi Setiawan, Atsushi Yamanaka   +3 more
doaj   +1 more source

Lipidated dengue-2 envelope protein domain III independently stimulates long-lasting neutralizing antibodies and reduces the risk of antibody-dependent enhancement. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Dengue virus is a mosquito-transmitted virus that can cause self-limiting dengue fever, severe life-threatening dengue hemorrhagic fever and dengue shock syndrome.
Chen-Yi Chiang, Chien-Hsiung Pan, Chun-Hsiang Hsieh, Jy-Ping Tsai, Mei-Yu Chen, Hsueh-Hung Liu, Shih-Jen Liu, Pele Chong, Chih-Hsiang Leng, Hsin-Wei Chen   +9 more
doaj   +1 more source

Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice [PDF]

, 2010
Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between levels of different chemokines in plasma and severity of dengue.
Mauro M Teixeira, Besnard, Anne-Gaëlle, Danielle G Souza, Fagundes, C.T., Teixeira, Mauro M, Guabiraba Rodrigo, Fagundes Caio T., Teixeira Mauro M., Anne-Gaëlle Besnard, Souza, Danielle G., Souza Danielle G., Danielle G. Souza, Mauro M. Teixeira, Teixeira, M.M., Caio T Fagundes, Ryffel Bernhard, Bernhard Ryffel, Souza, Danielle G, Besnard, A., Marques, Rafael Elias, Fagundes, Caio T., Ryffel, Bernhard, Rodrigo Guabiraba, Fagundes, Caio T, Marques Rafael Elias, Marques, R.E., Guabiraba, Rodrigo, Guabiraba Brito, R., Besnard Anne-Gaëlle, Rafael Elias Marques, Caio T. Fagundes   +30 more
core   +1 more source

Development of Dengue virus type 2 replicons capable of prolonged expression in host cells

BMC Microbiology, 2001
Background As part of a program to develop a Dengue virus vaccine which avoids the deleterious effects of antibody dependent enhancement (ADE) of infection mediated by antibodies to Dengue virus structural proteins, we have begun to investigate the ...
Dayton Andrew I, Zhang Mingjie, Pang Xiaowu   +2 more
doaj   +1 more source

Synthesis and Evaluation of Aromatic Sulfonamide and Disulfonamide Derivatives as Dengue Virus NS3-NS5 Interaction Inhibitors. [PDF]

ChemMedChem
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Janáč J, Drahorád J, Harvalík J, Horáčková T, Brinker M, Loregian A, Brancale A, Mercorelli B, Cuřínová P.   +8 more
europepmc   +2 more sources

System Analysis of Dengue Virus Surveillance in BBTKL PP Surabaya Year 2012–2014

Jurnal Berkala Epidemiologi, 2015
Changing the distribution of dengue virus serotypes has occurred in Indonesia. This condition should be monitored continuously through the Dengue Virus Surveillance. Implementation of Dengue Virus Surveillance also conducted by BBTKL PP Surabaya.
Atina Husnayain, Kurnia Dwi Artanti, Acub Zaenal   +2 more
doaj   +1 more source

Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression

, 2005
Type 1 interferons (IFN-?/?) are key mediators of innate antiviral responses but havelittle effect on established replication of dengue viruses, which are mosquito-borneflaviviruses of immense global health importance.
Jones, M, Jacobs, M, Ball, S, Hibbert, L, Foster, G, Davidson, AD, Foster, GR, Davidson, A, Gruenwald, P, Schlaak, J   +9 more
core   +1 more source

Models of dengue virus infection [PDF]

Drug Discovery Today: Disease Models, 2006
The need for models of dengue disease has reached a pinnacle as the transmission of this mosquito-borne virus has increased dramatically. Little is known about the mechanisms that lead to dengue fever and its more severe form, dengue hemorrhagic fever; this is owing to the fact that only humans show signs of disease.
Dennis A, Bente, Rebeca, Rico-Hesse
openaire   +2 more sources