Results 61 to 70 of about 172,035 (288)

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

open access: yesAdvanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang   +10 more
wiley   +1 more source

Prospek Pemanfaatan Radiasi dalam Pengendalian Vektor Penyakit Demam Berdarah Dengue [PDF]

open access: yes, 2005
PENDAHULUANPenyakit Demam Berdarah Dengue (DBD) atau Dengue Haemorrhagic Fever (DHF) dapat bermanifestasi sebagai Dengue Shock Syndrome (DSS) yang merupakan suatu penyakit infeksi akibat virus dengue, ditularkan melalui gigitan vektor nyamuk Aedes ...
Nurhayati, S. (Siti)
core  

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki   +3 more
wiley   +1 more source

REVIEW ARTICLE: DEVELOPEMENT AND USING DENGUE VACCINE FOR DENGUE INFECTION VIRUS

open access: yesMedical and Health Science Journal, 2019
: Tropical and subtropical countries are regions with high incidence of dengue infection. Dengue virus infection is estimated to cause 300 million new infections in one year and approximately 1 million severe cases with 2 + 5% deaths.
Firdaus Kabiru Massey, Rika Yulia
doaj   +1 more source

Zika virus and the never-ending story of emerging pathogens and transfusion medicine [PDF]

open access: yes, 2016
In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses.
Grazzini, Giuliano   +4 more
core   +1 more source

Immunopathogenesis of Dengue Virus Infection

open access: yesJournal of Biomedical Science, 2001
Dengue virus infection causes dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS), whose pathogeneses are not clearly understood. Current hypotheses of antibody-dependent enhancement, virus virulence, and IFN-gamma/TNFalpha-mediated immunopathogenesis are insufficient to explain clinical manifestations of DHF/DSS such as ...
H Y, Lei   +5 more
openaire   +2 more sources

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao   +9 more
wiley   +1 more source

Serotype and Clinical Performance of Dengue Virus Infection on the Year 2009

open access: yesIndonesian Journal of Tropical and Infectious Disease, 2010
Dengue hemorrhagic fever is one of the important health problem in Indonesia, mortality rate is becoming decrease but many dengue shock syndrome cases is very difficult to be help.
Soegeng Soegijanto   +3 more
doaj   +1 more source

The Effect of Rekattidiri Ovitrap Towards Aedes Aegypti Larval Density [PDF]

open access: yes, 2017
Dengue Hemorrhagic Fever (DHF) is a health problem in Indonesia. The entire region of Indonesia at risk of contracting dengue disease. The study aims to prove the effect of modifications ovitrap rekattidiri on the density of larvae (HI: House Index, CI ...
Hadisaputro, S. (Soeharyo)   +3 more
core   +2 more sources

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