Results 61 to 70 of about 169,398 (330)

Autophagy Activation Induces p62-Dependent Autophagic Degradation of Dengue Virus Capsid Protein During Infection

Frontiers in Microbiology, 2022
In the past decade, dengue virus infection is one of the most prevalent and rapidly spreading arthropod-borne diseases worldwide with about 400 million infections every year.
Yaoxing Wu, Tao Zhou, Jiajia Hu, Yishan Liu, Shouheng Jin, Jianfeng Wu, Xiangdong Guan, Jun Cui   +7 more
doaj   +1 more source

A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis [PDF]

, 2017
The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium.
Diamond, Michael S, Dowd, Kimberly A, Goo, Leslie, Pierson, Theodore C, VanBlargan, Laura A   +4 more
core   +5 more sources

Wafer‐Scale Integration of α‐quartz Thin Films toward Super High Frequency Piezoelectric bioNEMS for Chikungunya Virus Detection

Advanced Functional Materials, EarlyView.
Epitaxial piezoelectric α‐quartz/Si BioNEMS sensors, made using soft chemistry, effectively detect the Chikungunya virus. They have a mass sensitivity of 205 pg Hz−1 in liquid and can detect the virus at a limit of 9 ng mL−1. This development enables high‐frequency mass devices for point‐of‐care testing in healthcare and other electronic applications ...
Raissa Rathar, Sijie Ding, David Sanchez‐Fuentes, Claire Jolly, Charlotte André‐Arpin, Rudy Desgarceaux, Nicolas Guillaume, Gustavo Ardila, Ricardo Garcia‐Bermejo, Jaume Gazquez, Sergi Plana‐Ruiz, Laura Picas, Adrian Carretero‐Genevrier   +12 more
wiley   +1 more source

The monocyte-macrophage-mast cell axis in dengue pathogenesis

Journal of Biomedical Science, 2018
Dengue virus, the causative agent of dengue disease which may have hemorrhagic complications, poses a global health threat. Among the numerous target cells for dengue virus in humans are monocytes, macrophages and mast cells which are important ...
Shu-Wen Wan, Betty A. Wu-Hsieh, Yee-Shin Lin, Wen-Yu Chen, Yan Huang, Robert Anderson   +5 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Reverse genetics rescue of sylvatic dengue viruses

Journal of Virology
There are an unknown number of sylvatic (“sylvan” = “of the forest”) dengue viruses currently being sustained by nonhuman primates and mosquitoes in the forests of Africa and Asia.
Paul Gendler, Arturo Barbachano-Guerrero, Samuel D. Chappell, Oshani C. Ratnayake, Samantha M. Pinto, Rushika Perera, Sara L. Sawyer   +6 more
doaj   +1 more source

Association of Dengue Virus Serotypes 1&2 with Severe Dengue Having Deletions in Their 3′Untranslated Regions (3′UTRs)

Microorganisms, 2023
Dengue virus infections are recorded as hyper-endemic in many countries, including India. Research pertaining to the reasons for frequent outbreaks and severe dengue is ongoing.
Deepti Maisnam, Arcy Billoria, V. S. V Prasad, Musturi Venkataramana   +3 more
doaj   +1 more source

The impact of the demographic transition on dengue in Thailand: Insights from a statistical analysis and mathematical modeling [PDF]

, 2009
Background: An increase in the average age of dengue hemorrhagic fever (DHF) cases has been reported in Thailand. The cause of this increase is not known.
A Nisalak, Aidan McDermott, Ananda Nisalak, BT Grenfell, C Torrence, CP Farrington, D Schenzle, DAT Cummings, DAT Cummings, DB Fischer, Derek A. T. Cummings, DJD Earn, Donald S. Burke, DS Burke, GN Malavige, H Muench, HJ Wearing, Jeremy Farrar, JR Williams, Justin T. Lessler, K Kongsomboon, KT Thai, MG Guzman, N Ferguson, NM Ferguson, O Chareonsook, O Wichmann, P Manfredi, R Reves, Richard G. Jarman, RM Anderson, Robert V. Gibbons, Rungnapa Prasanthong, SB Halstead, SB Halstead, Sopon Iamsirithaworn, TP Endy, Y Nagao, Y Nagao   +38 more
core   +6 more sources

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Prospek Pemanfaatan Radiasi dalam Pengendalian Vektor Penyakit Demam Berdarah Dengue [PDF]

, 2005
PENDAHULUANPenyakit Demam Berdarah Dengue (DBD) atau Dengue Haemorrhagic Fever (DHF) dapat bermanifestasi sebagai Dengue Shock Syndrome (DSS) yang merupakan suatu penyakit infeksi akibat virus dengue, ditularkan melalui gigitan vektor nyamuk Aedes ...
Nurhayati, S. (Siti)
core