Results 71 to 80 of about 7,980 (172)
VIRUS, 1957 Electron micrographs of dengue viruses of Hawaiian strain and Mochizuki strain, which were adapted to mouse brain and chick embryo have been taken using purified virus materials.Purification methods employed were as follows: (I) Combination of partial purification of the virus adsorption to and elution from erythrocytes and ultracentrifuge, (2 ...
YOH NAKAGAWA, MASAHISA SHINGU
openaire +3 more sources
Liver Organoids: From Disease Modelling to Regenerative Medicine
Cell Proliferation, EarlyView.Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang +5 more
wiley +1 more source
Roles for Endothelial Cells in Dengue Virus Infection
Advances in Virology, 2012 Dengue viruses cause two severe diseases that alter vascular fluid barrier functions, dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). The endothelium is the primary fluid barrier of the vasculature and ultimately the effects of dengue ...
Nadine A. Dalrymple, Erich R. Mackow
doaj +1 more source
Jurnal Vektor Penyakit, 2017 Dengue hemorrhagic fever is still one of the major public health problem worldwide, particularly in sub tropical and tropical regions. The disease is caused by the presence of dengue virus infection (DENVa), member of the Flaviviridae family.
Triwibowo Ambar Garjito
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Early tocilizumab and outcomes in acute necrotizing encephalopathy
Developmental Medicine &Child Neurology, EarlyView.Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han +14 more
wiley +1 more source
Dengue Virus Infection in Africa
Emerging Infectious Diseases, 2011 Reported incidence of dengue has increased worldwide in recent decades, but little is known about its incidence in Africa. During 1960-2010, a total of 22 countries in Africa reported sporadic cases or outbreaks of dengue; 12 other countries in Africa reported dengue only in travelers.
Ananda Amarasinghe +3 more
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Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
The FEBS Journal, EarlyView.EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
The FEBS Journal, EarlyView.C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
The FEBS Journal, EarlyView.This review summarizes recent structures of the UBR4 complex, a giant E4 ubiquitin ligase which recognizes proteins with pre‐existing ubiquitin modifications and marks them for degradation. The UBR4 complex uses a large arena lined with substrate interaction modules to select features on ubiquitinated substrates, such as the presence of N‐degrons or ...
Daniel B. Grabarczyk, Tim Clausen
wiley +1 more source
UPDATE MANAGEMENT OF DENGUE COMPLICATION IN PEDIATRIC
Indonesian Journal of Tropical and Infectious Disease, 2015 Dengue virus infection is one of the important health problems in Indonesia, although the mortality rate has been decreased but many dengue shock syndrome cases is very difficult to be solving handled.
Soegeng Soegijanto
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