Results 111 to 120 of about 161,991 (287)

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

On Improving the Performance of Kalman Filter in Denoising Oil Palm Hyperspectral Data

Agriculture
A common drawback of denoising methods of images is that all pixels are filtered regardless of the amount of noise affecting them individually. Since the essence of denoising is lowpass filtering, subjecting clean pixels to denoising results in blurring.
Imanurfatiehah Ibrahim, Hamzah Arof, Mohd Izzuddin Anuar, Mohamad Sofian Abu Talip   +3 more
doaj   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Retinal OCT Images: Graph-Based Layer Segmentation and Clinical Validation

Applied Sciences
Spectral-domain Optical Coherence Tomography (SD-OCT) is a critical tool in ophthalmology, providing high-resolution cross-sectional images of the retina.
Priyanka Roy, Mohana Kuppuswamy Parthasarathy, Vasudevan Lakshminarayanan   +2 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Image Denoising using Optimally Weighted Bilateral Filters: A Sure and Fast Approach

, 2015
The bilateral filter is known to be quite effective in denoising images corrupted with small dosages of additive Gaussian noise. The denoising performance of the filter, however, is known to degrade quickly with the increase in noise level.
Chaudhury, Kunal N., Rithwik, Kollipara
core  

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source

Adaptive SVD Denoising in Time Domain and Frequency Domain

Applied Sciences
In seismic data processing, noise not only affects velocity analysis and seismic migration, but also causes potential risks in post-stack processing because of the artifacts.
Meixuan Ren, Enli Zhang, Qiang Kang, Long Chen, Min Zhang, Lei Gao   +5 more
doaj   +1 more source

Frequency Domain Based Approach for Denoising of Underwater Acoustic Signal Using EMD

Journal of Intelligent Systems, 2013
Underwater communication is usually affected by ambient noise, which may be generated by different sources, such as the wind origin sea-surface sources, ships and under water life.
Veeraiyan Vijayabaskar, Velayutham Rajendran, Philip Mathews M.   +2 more
doaj   +1 more source