Results 101 to 110 of about 7,500 (302)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A Denotational Semantics for Circus
AbstractCircus specifications define both data and behavioural aspects of systems using a combination of Z and CSP. Previously, a denotational semantics has been given to Circus; however, as a shallow embedding of Circus in Z, it was not possible to use it to prove properties like the refinement laws that justify the distinguishing development ...
Marcel Oliveira +2 more
openaire +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Nuclear denotation and increased incidence of cancer: A present concern in cancer research
The recent destruction of the nuclear electricity plant in Japan has led to nuclear leakage. The nuclear denotation has become the present issue of concern. In oncology, there is no doubt that exposure to nuclear leakage can cause cancer.
Wiwanitkit, Viroj
core +1 more source
The article deals with the feature of prose by M. I. Tsvetaeva, based on the system of defining. The author defines such concepts as denotation, signified contextual metadefinition and relative definition.
O. S. Gavrilova
doaj
English partitives in Functional Discourse Grammar: types and constraints
The aim of this paper is to provide a unified analysis of partitive constructions like one/some of the boxes which, unlike previous accounts, succeeds in accounting for (i) both their internal structure and the constraints on the embedded NP, and (ii ...
Evelien Keizer
doaj +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Anglo-Irish twentieth century writer Elizabeth Bowen is a wellknown stylist, that is why the formal analysis of the fragments of the novels is of great interest. ‘Close-reading’, invented and brought into light by the “new critics” in the XX century,
Maria A. Rodina
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

