Results 101 to 110 of about 7,500 (302)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Denotational Semantics for Circus

open access: yesElectronic Notes in Theoretical Computer Science, 2007
AbstractCircus specifications define both data and behavioural aspects of systems using a combination of Z and CSP. Previously, a denotational semantics has been given to Circus; however, as a shallow embedding of Circus in Z, it was not possible to use it to prove properties like the refinement laws that justify the distinguishing development ...
Marcel Oliveira   +2 more
openaire   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Nuclear denotation and increased incidence of cancer: A present concern in cancer research

open access: yes, 2012
The recent destruction of the nuclear electricity plant in Japan has led to nuclear leakage. The nuclear denotation has become the present issue of concern. In oncology, there is no doubt that exposure to nuclear leakage can cause cancer.
Wiwanitkit, Viroj
core   +1 more source

THE TYPOLOGY OF PROSE METADEFINITIONS OF M. I. TSVETAEVA OF THE THEMATIC GROUP WITH AN INVARIANT MEANING OF "SCIENCE"

open access: yesГуманитарные и юридические исследования, 2021
The article deals with the feature of prose by M. I. Tsvetaeva, based on the system of defining. The author defines such concepts as denotation, signified contextual metadefinition and relative definition.
O. S. Gavrilova
doaj  

English partitives in Functional Discourse Grammar: types and constraints

open access: yesGlossa, 2017
The aim of this paper is to provide a unified analysis of partitive constructions like one/some of the boxes which, unlike previous accounts, succeeds in accounting for (i) both their internal structure and the constraints on the embedded NP, and (ii ...
Evelien Keizer
doaj   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Close-Reading’ and its Role for the Interpretation of E. Bowen’s Novels The Last September and To The North

open access: yesИзвестия Южного федерального университета: Филологические науки, 2019
The Anglo-Irish twentieth century writer Elizabeth Bowen is a wellknown stylist, that is why the formal analysis of the fragments of the novels is of great interest. ‘Close-reading’, invented and brought into light by the “new critics” in the XX century,
Maria A. Rodina
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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