Results 241 to 250 of about 588,860 (289)

Lysozyme-Associated Nephropathy in Myeloid Neoplasms: A Clinicopathological and Mass Spectrometric Study of Two Cases.

Nephron
Matsumoto M, Yamamoto S, Shinkawa K, Matsubara T, Takeda J, Kitawaki T, Arai Y, Teramoto Y, Minamiguchi S, Kanetsuna Y, Joh K, Yamaguchi Y, Kang D, Honda K, Mii A, Shimizu A, Ubara Y, Yanagita M.   +17 more
europepmc   +1 more source

Molecular Defects That Affect Platelet Dense Granules

Seminars in Thrombosis and Hemostasis, 2004
Platelet dense granules form using mechanisms shared by melanosomes in melanocytes and by subsets of lysosomes in more generalized cells. Consequently, disorders of platelet dense granules can reveal how organelles form and move within cells. Models for the study of new vesicle formation include isolated delta-storage pool deficiency, combined ...
William A Gahl, Marjan Huizing, Meral Gunay-Aygun   +2 more
exaly   +4 more sources

Dense Granules: Are They Key Organelles to Help Understand the Parasitophorous Vacuole of All Apicomplexa Parasites?

International Journal for Parasitology, 2005
Together with micronemes and rhoptries, dense granules are specialised secretory organelles of Apicomplexa parasites. Among Apicomplexa, Plasmodium represents a model of parasites propagated by way of an insect vector, whereas Toxoplasma is a model of ...
Walter Däubener
exaly   +2 more sources

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The very dense granule in rabbit platelets

Journal of Ultrastructure Research, 1968
The morphology of the very dense granule in rabbit platelets is defined after fixation in glutaraldehyde, and acetaldehyde with or without OsO 4 postfixation. The granules are best preserved by glutaraldehyde and OsO 4 . An unsubstituted amine has been localized within the granule by histochemical methods.
M D, Silver, H A, Gardner
openaire   +2 more sources

Dense-Core Secretory Granule Biogenesis

Physiology, 2006
The dense-core secretory granule is a key organelle for secretion of hormones and neuropeptides in endocrine cells and neurons, in response to stimulation. Cholesterol and granins are critical for the assembly of these organelles at the trans-Golgi network, and their biogenesis is regulated quantitatively by posttranscriptional and posttranslational ...
Taeyoon, Kim, Marjorie C, Gondré-Lewis, Irina, Arnaoutova, Y Peng, Loh   +3 more
openaire   +2 more sources

The role of Rab38 in platelet dense granule defects

Journal of Thrombosis and Haemostasis, 2008
The fawn-hooded hypertensive (FHH) rat has a mutation in the Rab38 gene that is associated with a platelet dense granule storage pool disease.To better characterize the expression and function of Rab38 in FHH rat and human megakaryocytes and platelets.Rab38 expression in FHH rat and normal tissues was demonstrated by western blotting.
I, Ninkovic, J G, White, A, Rangel-Filho, Y H, Datta   +3 more
openaire   +2 more sources

Platelet aggregation and dense granule secretion in schizophrenia

Psychiatry Research, 1994
The functional state of platelets and their possible impairment in response to various stimuli were assessed in saline-diluted citrated blood samples of normal male control subjects (n = 27), and in schizophrenic patients with (n = 34) and without (n = 23) haloperidol treatment.
J K, Yao, D P, van Kammen, J, Gurklis, J L, Peters   +3 more
openaire   +2 more sources

Comparative study of platelet dense granule constituents

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1982
Cat, cattle, dog, horse, human, mink, pig, and rabbit platelets were separated from plasma by gel filtration. The gel-filtered platelets (GFP) were treated with thrombin to induce maximal granule secretion and the potential dense granule constituents ATP, ADP, serotonin (5-HT), Ca2+, and Mg2+ were measured in GFP and in the control and thrombin-treated
K M, Meyers, H, Holmsen, C L, Seachord
openaire   +2 more sources

The Nature of Breast Dense Core Granules: Uranaffin Reactivity

Histopathology, 1987
In this study breast tissue that contained ultrastructural dense core granules has been examined from 24 patients. The possible neuroendocrine characteristics of the granules were studied using the uranaffin reaction and an ultrastructural argyrophil stain. The tissue included 15 breast carcinomas and nine benign samples. Two types of breast dense core
T J Anderson, T J Anderson
exaly   +3 more sources