Results 41 to 50 of about 588,860 (289)

Timing of dense granule biogenesis in asexual malaria parasites

open access: yesMicrobiology, 2023
ABSTRACT Malaria is an important infectious disease that continues to claim hundreds of thousands of lives annually. The disease is caused by infection of host erythrocytes by apicomplexan parasites of the genus Plasmodium .
Tansy Vallintine, Christiaan van Ooij
openaire   +2 more sources

Spray freeze granulation of submicron alumina and its sintering behavior via spark plasma sintering [PDF]

open access: yesScience of Sintering, 2015
Spray freeze granulation is an improved method based on spray granulation, solving many limitations of spray granulation. In this work, spray freeze granulation of submicron alumina is performed to explore the possibility of industrial-scale ...
Liu Wei, Xie Zhipeng
doaj   +1 more source

Robocasting of dense zirconia parts using commercial yttria-stabilized zirconia granules and ultrafine particles. Paste preparation, printing, mechanical properties

open access: yes, 2022
In this work, a commercial 3 mol% yttrium oxide partially stabilized zirconia spray-dried granules were used as such, and after intensive milling, for the production of dense samples by robocasting technique.
Becker G.   +11 more
core   +1 more source

Generation of Hermansky Pudlak syndrome type 2 (HPS2) induced pluripotent stem cells (iPSCs)

open access: yesStem Cell Research, 2016
Hermansky–Pudlak syndrome type 2 (HPS2) is a rare autosomal recessive disorder resulting from functional mutations in the adaptor-related protein complex 3, beta 1 subunit (AP3B1) gene.
Jean Ann Maguire   +5 more
doaj   +1 more source

Platelet proteome and function in X−linked thrombocytopenia with thalassemia and in silico comparisons with gray platelet syndrome

open access: yesHaematologica, 2020
In X-linked thrombocytopenia with thalassemia (XLTT; OMIM 314050), caused by the mutation p.R216Q in exon 4 of the GATA1 gene, male hemizygous patients display macrothrombocytopenia, bleeding diathesis and a b-thalassemia trait.
Daniel Bergemalm   +8 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Localization of the small monomeric GTPases Rab3D and Rab3A in the AtT- 20 rat pituitary cell line

open access: yesEuropean Journal of Histochemistry, 2009
We investigated the cellular localization of the small GTPases Rab3D and Rab3A in AtT-20 cells treated with the drug Brefeldin A. Brefeldin A induces the redistribution of the Golgi complex into the endoplasmic reticulum and tubulation of endosomes ...
G Tabellini   +6 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Kinetics of permeability changes induced by electric impulses in chromaffin granules [PDF]

open access: yes, 1977
Lindner P, Neumann E, Rosenheck K. Kinetics of permeability changes induced by electric impulses in chromaffin granules. Journal of Membrane Biology. 1977;32(1):231-254.Electric field pulses, ranging in intensity from 20 to 50 kV/cm and in duration from ...
Lindner, P.   +2 more
core   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

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