Results 51 to 60 of about 588,860 (289)

Generation and analysis of mouse lines with a defect in platelet secretion and application in mouse models of atherosclerosis and tumor metastasis [PDF]

, 2013
Introduction: The involvement of platelets in various diseases has been increasingly recognized in the recent decades. This contribution is believed to involve platelet secretion and formation of reactive microparticles.
Schumacher, Dagmar
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Electron Dense Granules in Yoghurt: Characterization by X-ray Microanalysis [PDF]

, 1986
A study was undertaken to investigate the influence of buffer composition, pH and glutaraldehyde fixation time on the appearance of electron dense granules in yoghurt.
Humphrey, Richard, Kakuda, Yukio, Parnell-Clunies, Estelle M.   +2 more
core   +1 more source

Platelet Delta (δ)-Storage Pool Deficiency: A Case Series and Review of the Literature

Hematology Reports, 2023
Hereditary platelet delta (δ)-storage pool deficiency is a rare condition in which there are fewer dense granules in platelets disrupting primary hemostasis.
Amir F. Beirat, Sasmith R. Menakuru, Maitri Kalra   +2 more
doaj   +1 more source

DGPD: a knowledge database of dense granule proteins of the Apicomplexa

Database, 2022
Abstract Apicomplexan parasites cause severe diseases in human and livestock. Dense granule proteins (GRAs), specific to the Apicomplexa, participate in the maintenance of intracellular parasitism of host cells. GRAs have better immunogenicity and they can be emerged as important players in vaccine development.
Hang Hu 0016, Zhenxiao Lu, Haisong Feng, Guojun Chen, Yongmei Wang, Congshan Yang, Zhenyu Yue   +6 more
openaire   +3 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Ultrastructural study on the granulocytes of Uttara fowl (Gallus domesticus) [PDF]

Veterinary World, 2016
Aim: The present study was conducted to know the ultrastructural detail of the blood cells of Uttara fowl (native fowl of Uttarakhand). Materials and Methods: The experiment was conducted on 10 apparently healthy adult birds of either sex reared at the ...
Khan Idrees Mohd, Meena Mrigesh, Balwinder Singh, Ishwar Singh   +3 more
doaj   +1 more source

Designing slurry conditions to control size distribution of spray‐dried dense YSZ granules

, 2023
This study suggests approaches to achieve the desired size and size distribution of highly dense spherical granules by investigating the effect of slurry conditions on size distribution.
Hyun‐Ae Cha, Cheol‐Woo Ahn, Byung‐Dong Hahn, Hahn, Byung-Dong, Kyung‐Chan Shin, Hee‐Jin Son, Ahn, Cheol-Woo, Kim, Do Kyung, Shin, Kyung-Chan, Do Kyung Kim, Cha, Hyun-Ae, Choi, Jong-Jin, Son, Hee-Jin, Jong‐Jin Choi   +13 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source