Results 81 to 90 of about 588,860 (289)

Dense-core granules: a specific hallmark of the neuronal/neurosecretory cell phenotype.

open access: yes, 2004
Expression of dense-core granules, a typical exocytic organelle, is widely believed to be controlled by coordinate gene expression mechanisms specific to neurones and neurosecretory cells.
Giordano T   +3 more
core   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

open access: yesAdvanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye   +11 more
wiley   +1 more source

TgPP6C deletion has no notable effects on the structure of T. gondii rhoptries, dense granules, apicoplast, mitochondria or micronemes.

open access: yes, 2023
IMC1 (green) and DAPI (blue) stains were used to denote the parasites and nuclei (DNA), respectively. Anti-ARO, anti-GRA32, anti-CPN60, anti-HSP60 and anti-MIC2 antibodies were used to stain the rhoptries, dense granules, apicoplast, mitochondria and ...
Qin-Li Liang (5689277)   +9 more
core   +1 more source

Ferroionic‐Assisted, Charge‐Driven Polymorphic Phase Engineering for Multilevel Memristive Devices

open access: yesAdvanced Materials, EarlyView.
A CuInP2S6/Mo0.92W0.08Te2 heterostructure enables a gradual semiconductor‐to‐semimetal phase transition through Cu+ ion migration and charge accumulation. The spatially engineered 2H/1T′ mixed phases produce continuously tunable conductance states in a two‐terminal geometry, while suppressing depolarizing fields and stabilizing the metastable 1T′ phase.
Nayeon Kim   +9 more
wiley   +1 more source

Phosphotyrosine proteins in platelets from patients with storage pool disease: direct relation between granule defects and defective signal transduction

open access: yesHaematologica, 2002
BACKGROUND AND OBJECTIVES: Storage pool diseases (SPD) are heterogeneous disorders associated with an abnormal presence of intraplatelet granules, which cause mild to moderate bleeding diathesis. We investigated signaling through tyrosine phosphorylation
G Arderiu   +5 more
doaj  

Assessment of bacterial and structural dynamics in aerobic granular biofilms

open access: yesFrontiers in Microbiology, 2013
Aerobic granular sludge is based on self-granulated flocs forming mobile biofilms with a gel-like consistence. Bacterial and structural dynamics from flocs to granules were followed in anaerobic-aerobic sequencing batch reactors fed with synthetic ...
David G. Weissbrodt   +4 more
doaj   +1 more source

Interface Dynamics in Biomolecular Condensates by High‐Speed AFM

open access: yesAdvanced Materials Interfaces, EarlyView.
High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria   +6 more
wiley   +1 more source

Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranes

open access: yesThe EMBO Journal
Secretory proteins aggregate into non-soluble dense-core granules in recycling endosome-like compartments prior to regulated release. By contrast, aberrantly processed, secreted amyloid-β (Aβ) peptides derived from amyloid precursor protein (APP) form ...
Preman J Singh   +13 more
doaj   +1 more source

Granular-based dense crowd density estimation

open access: yes, 2018
Dense crowd density estimation is one of the fundamental tasks in crowd analysis. While tremendous progress has been made to understand crowd scenes along with the rise of Convolutional Neural Networks (CNNs), research work on dense crowd density ...
Chan, Chee Seng, Kok, Ven Jyn
core   +1 more source

Scalable Fabrication of Chemically Stabilized Gelatin Hydrogel Fibers by Thermal Drawing

open access: yesAdvanced Materials Interfaces, EarlyView.
Scalable processing of hydrogel fibers remains a major challenge. By coupling thermal drawing with Maillard chemistry, a transient viscous‐flow window is created that enables continuous fabrication of microstructured gelatin fibers tens of meters long, while continued in situ crosslinking during drawing stabilizes the fibers for physiological ...
Chaoqun Dong   +5 more
wiley   +1 more source

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