Results 41 to 50 of about 121,711 (277)
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Use of Spinning Rollers for Surface Densification of Wood
Drvna IndustrijaIn this study, softwood cedar of Lebanon (Cedrus libani A.Rich.) and hardwood black poplar (Populus nigra L.), turned into cylinders by turning, were subjected to a surface densification process.
Zafer Kaya, Sait Dündar Sofuoğlu
doaj +1 more source
Life Cycle Perspectives of Using Non-Pelleted vs. Pelleted Corn Stover in a Cellulosic Biorefinery
Energies, 2021 Cellulosic biorefineries have attracted interest due to the growing energy security and environmental concerns related to fossil fuel-based energy and chemicals.
Nurun Nahar +4 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The Implications of Densification Policies for Greater Resistencia (Argentina): an Assessment of Recent Experience [PDF]
, 2014 . Since 2001, Resistencia City Council has been promoting growth in building height by steering development towards built-up areas in central districts that already have complete infrastructure, through the implementation of the Ordinance 5403/01 - high ...
Schneider, V. (Valeria)
core
Hypergraph Theory: Applications in 5G Heterogeneous Ultra-Dense Networks
, 2017 Heterogeneous ultra-dense network (HUDN) can significantly increase the spectral efficiency of cellular networks and cater for the explosive growth of data traffic in the fifth-generation (5G) communications.
Li, Geoffrey Ye +3 more
core +1 more source
Sintering and densification of nanocrystalline ceramic oxide powders: a review [PDF]
, 2008 Observation of the unconventional properties and material behaviour expected in the nanometre grain size range necessitates the fabrication of fully dense bulk nanostructured ceramics.
Chaim, Rachman +3 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Mechanical properties and energy absorbing capabilities of Z-pinned aluminum foam sandwich [PDF]
, 2019 Aluminum foam sandwich (AFS) structures are suitable for impact protection in lightweight structural components due to their specific energy absorption capability under compression.
Kadkhodapour, Javad +2 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source