Results 51 to 60 of about 135,780 (323)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Plasticity of nanocrystalline zirconia ceramics and composites [PDF]
, 1997 The deformation strain rate of nanocrystalline Y-TZP shows an increase by a factor 4 if the grain size decreases from 200 to 100 nm. Real superplastic deformation (strain rate > 10−4 s−1) is observed in these materials at relative low temperature (1100 ...
Boutz, M.M.R. +4 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Communication, 2014 The author questions the notion of power as it relates to TV series. He rejects the concept of the all-powerful, deceiving cultural industry. The kind of power a TV series may exert lies in its ability to maintain its viewers in a state of fictional ...
Jean-Pierre Esquenazi
doaj +1 more source
Asymptotic Behavior of Ultra-Dense Cellular Networks and Its Economic Impact [PDF]
, 2014 This paper investigates the relationship between base station (BS) density and average spectral efficiency (SE) in the downlink of a cellular network. This relationship has been well known for sparse deployment, i.e.
Kim, Seong-Lyun +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Compacting the city centre: densification in two Newcastles
Buildings & Cities, 2021 The compact city and the associated process of densification have attained almost hegemonic status as a sustainable urban form. Seeking to counteract the negative impacts of sprawl, urban densification has usually focused on areas beyond the city centre.
Bob Giddings, Robert Rogerson
doaj +1 more source
Full-Densification of SLS Parts by Re-Melting [PDF]
, 2004 Among commercially available rapid prototyping processes, SLS is the most effective in terms of adaptability of various materials. However, rapid prototyped parts by the process are always porous and the physical properties of the parts are different ...
Niino, T., Yamada, H.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source