Results 51 to 60 of about 52,379 (308)

Fabrication Of y-TiAl Intermetallic Alloys Via Hot Pressing Technique. [PDF]

open access: yes, 2004
Gamma titanium-aluminide (y-TiAl) based alloys are potentially suitable as advanced structural materials for high performance applications such as components in aerospace vehicles, aircraft turbine, and automotive engines due to their unique and superior
Astrawinata, Rizal   +2 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sustainable densification of the deep crust

open access: yes, 2020
International audienceThe densification of the lower crust in collision and subduction zones plays a key role in shaping the Earth by modifying the buoyancy forces acting at convergent boundaries. It takes place through mineralogical reactions, which are
Podladchikov, Yury, y   +15 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Pouvoir des séries télévisées

open access: yesCommunication, 2014
The author questions the notion of power as it relates to TV series. He rejects the concept of the all-powerful, deceiving cultural industry. The kind of power a TV series may exert lies in its ability to maintain its viewers in a state of fictional ...
Jean-Pierre Esquenazi
doaj   +1 more source

Sintering and densification mechanisms of Y2BaCuO5 pellets

open access: yes, 1999
The sintering and densification of YBaCuO (Y-211) pellets made from powders with different characteristics have been investigated in the temperature range 1000-1140°C.
Ilyushechkin, A.   +7 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Compacting the city centre: densification in two Newcastles

open access: yesBuildings & Cities, 2021
The compact city and the associated process of densification have attained almost hegemonic status as a sustainable urban form. Seeking to counteract the negative impacts of sprawl, urban densification has usually focused on areas beyond the city centre.
Bob Giddings, Robert Rogerson
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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