Results 71 to 80 of about 121,711 (277)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Review on Binder Jet Additive Manufacturing of 316L Stainless Steel

Journal of Manufacturing and Materials Processing, 2019
Binder jet additive manufacturing enables the production of complex components for numerous applications. Binder jetting is the only powder bed additive manufacturing process that is not fusion-based, thus manufactured parts have no residual stresses as ...
Saereh Mirzababaei, Somayeh Pasebani
doaj   +1 more source

Elementary processes governing the evolution of road networks [PDF]

, 2012
Urbanisation is a fundamental phenomenon whose quantitative characterisation is still inadequate. We report here the empirical analysis of a unique data set regarding almost 200 years of evolution of the road network in a large area located north of ...
BLII Turner, C Dye, CE Ramalho, D Balcan, E Glaeser, F Xie, F Xie, H Taubenbck, HA Makse, I Barnes, LC Freeman, LMA Bettencourt, LMA Bettencourt, M Barthelemy, M Barthelemy, M Batty, P Crucitti, P Hall, RI McDonald, S Lammer, S Porta, T Courtat, V Latora   +22 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Strengthening of Wood-Like Materials via Densification and Nanoparticle Intercalation

Nanomaterials, 2020
Recently, several chemical and physical treatments were developed to improve different properties of wood. Such treatments are applicable to many types of cellulose-based materials.
David Novel, Simone Ghio, Andrea Gaiardo, Antonino Picciotto, Vincenzo Guidi, Giorgio Speranza, Maurizio Boscardin, Pierluigi Bellutti, Nicola M. Pugno   +8 more
doaj   +1 more source

Greater Resistencia Study Case: Greenfield and Increased Densification [PDF]

, 2012
. This paper focuses on one of the relevant issues of the phenomena of urban expansion and densification, i.e. the lack of planning of public greenfields.
Perez, M. (Malena), Schneider, V. (Valeria)   +1 more
core  

Effect of microstructure and temperature on the erosion rates and mechanisms of modified EB PVD TBCs [PDF]

, 2009
Thermal barrier coatings (TBCs) have now been used in gas turbine engines for a number of decades and are now considered to be an accepted technology. As there is a constant drive to increase the turbine entry temperature, in order to increase engine ...
Murphy, K. S., Nicholls, J. R., Wellman, R. G.   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Systematic Review of Socially Sustainable and Community Regeneration: Research Traits, Focal Points, and Future Trajectories

Buildings
Accelerated urbanization has led to regional disruptions and exacerbated imbalances in spatial quality, social cohesion, and inequalities. Urban regeneration, as a mitigating strategy for these disruptions, faces significant social challenges ...
Jiawei Hu, Jinliu Chen, Pengcheng Li, Jianxiong Yan, Haoqi Wang   +4 more
doaj   +1 more source