Results 111 to 120 of about 84,432 (239)
Cellular senescence induced by distinct stressors generated heterogeneous populations with variable expression of canonical biomarkers. Rapamycin showed selective senomorphic effects on specific subpopulations, while the senolytic agent ABT‐263 effectively eliminated all senescent cells, regardless of biomarker heterogeneity.
Vijayraghavan Seshadri+8 more
wiley +1 more source
THE RECOMBINATION OF OXYGEN ATOMS AT HIGH TEMPERATURES AS MEASURED BY SHOCK TUBE DENSITOMETRY
John H. Kiefer, Robert W. Lutz
openalex +2 more sources
Citrate, as a common food additive, provides the major cellular ATP source. This study demonstrates that dietary citrate attenuates common vascular diseases, including atherosclerosis and hypertension, and reduces frailty in mice by delaying vascular aging.
Ya Zhao+11 more
wiley +1 more source
Postnatal high fat (HF) feeding negatively impacts executive function in both adult and aged mice, but consumption of the same diet during the perinatal period only is beneficial in older age. Maternal HF diet is associated with increased cholinergic innervation of the prefrontal cortex of young, but not aged, offspring.
Laura Contu+3 more
wiley +1 more source
Clinical history including self‐reported history and oral food challenge outcome, and sIgE sensitization profile of 200 subjects with suspected fish allergy was analyzed to construct a 3‐step fish allergenicity ladder. The allergenicity ladder was positively linked to the relative parvalbumin content of fish muscle but not to differences in the IgE ...
Christine Y. Y. Wai+21 more
wiley +1 more source
Abstract Purpose To present the outcomes of a randomised clinical trial for the treatment of progressive keratoconus using different kinds of riboflavin and the addition of sterile water in thin corneae. Methods A randomised study using epithelium‐off corneal cross‐linking (CXL) with continuous UVA irradiance 9 mW/cm2 for 10 min (total fluence 5.4 J ...
Ingemar Gustafsson+5 more
wiley +1 more source
ABSTRACT Aim This study evaluated urinary calcium (Ca) and phosphorus (P) excretion in very low birth weight infants ( < 1500 g, VLBW) without severe morbidity, treated with methylxanthines. Methods Eighty‐one VLBW infants were analysed. Urinary Ca and P and their creatinine ratios were measured biweekly until day 56.
Tomas Matejek+5 more
wiley +1 more source
Background and Purpose Activation of Protein Phosphatase 2A (PP2A), via genetic and pharmacologic modulation of SET, has recently being identified as a promising strategy to therapeutically target acute myeloid leukaemia (AML) carrying KMT2A (MLL) chromosomal translocations (KMT2A‐r AML).
Yoana Arroyo‐Berdugo+11 more
wiley +1 more source