Results 111 to 120 of about 224,534 (289)
Visualizing and Quantifying microRNA‐Induced DNA Origami Separation at the Nanoscale
Angewandte Chemie, EarlyView.Clinically relevant miRNA biomarkers trigger the disassembly of DNA origami dimers into monomers through a toehold‐mediated strand displacement reaction. High‐speed AFM was used to visualize this reaction in real time, while solid‐state nanopore measurements quantified the populations of dimers and monomers, as well as the resulting miRNA concentration,
Chalmers C. C. Chau +4 more
wiley +2 more sources
Consortium PsychiatricumIn the article “Duration Matters: Anticonvulsant Therapy Linked to Bone Loss in Interim Cross-Sectional Study” by Natalia Sivakova et al., published in Consortium PSYCHIATRICUM journal (Volume 6 Issue 2), errors were identified that require correction.
Natalia A. Sivakova +8 more
doaj +1 more source
Advanced Science, EarlyView.This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang +13 more
wiley +1 more source
Normalization of spine densitometry
Journal of Bone and Mineral Research, 1994 Abstract We investigated several transformations of bone mineral content (BMC) and area density (BMD), in particular volumetric density (BMAD), to ascertain the influence on (1) body size dependence, (2) diagnostic sensitivity, and (3) precision.
R B, Mazess +3 more
openaire +2 more sources
Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL [PDF]
, 2015 In chronic lymphocytic leukemia (CLL), Notch1 and Notch2 signaling is constitutively activated and contributes to apoptosis resistance. We show that genetic inhibition of either Notch1 or Notch2, through small-interfering RNA, increases apoptosis of CLL ...
Baldoni, Stefano +9 more
core +3 more sources
Advanced Science, EarlyView.This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan +9 more
wiley +1 more source
Osteoporosis of the spine as a multidisciplinary problem and life condition of patients
Медицинский совет, 2015 Healthcare practitioners specializing in different areas deal with osteoporosis due to the growing incidence and prevalence of the disease as well as a variety of clinical manifestations.
V. G. Pomnikov +3 more
doaj +1 more source
AbstractThis chapter describes various densitometry techniques that involve measurement of photon absorption at a single energy and at multiple energies and measurement of differential photon attenuation across absorption edges. Covered in the chapter include single-line, multiple-energy, absorption-edge, and hybrid K-edge densitometry.
R. Venkataraman +3 more
openaire +1 more source
SUMOylation inhibits FOXM1 activity and delays mitotic transition [PDF]
, 2014 The forkhead box transcription factor FOXM1 is an essential effector of G2/M-phase transition, mitosis and the DNA damage response. As such, it is frequently deregulated during tumorigenesis. Here we report that FOXM1 is dynamically modified by SUMO1 but
Brosens, Jan J. +13 more
core +1 more source
Advanced Science, EarlyView.Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu +11 more
wiley +1 more source