Results 101 to 110 of about 248,416 (349)

THE USE OF TOOLS DENSITOMETRY IN THE QUANTITATIVE COMPUTATIONS OF PROTEIN FRACTIONS

Теория и практика переработки мяса, 2017
In the study of proteomic profiles of proteins, many scientists stop at the stage of obtaining the final data of the experiment in the form of gels. They have got no information on the possibilities and prospects concerning the application of modern ...
Natalia L. Vostrikova
doaj   +1 more source

Features of laboratory diagnostics of undifferentiated connective tissue dysplasia in women with genital prolapse

Медицинский совет, 2020
Introduction. The issues of connective tissue dysplasia are currently highly urgent, particularly when it comes to the increase in a woman’s life expectancy and high incidence rates of the disease.
G. I. Teleeva, L. S. Tselkovich
doaj   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Clinical and laboratory comparison in postmenopausal osteoporosis with normal and enhanced function of the parathyroid glands

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
The need for a comprehensive diagnostic approach to the patients suffering osteoporosis is determined by high medical and social significance and disabling nature of complications.
K. A. Saveleva, S. M. Kotova, N. A. Karlova, V. A. Koloskov, I. Yu. Matezius   +4 more
doaj   +1 more source

A survey on the possibility of utilizing γH2AX as a biodosimeter in radiation workers [PDF]

, 2015
Introduction DNA damage is among the main consequences of radiation. Of many different classes of DNA damage, double-strand breaks are the most deleterious.
Asadi, J., Khoshnazar, A.K., Mir, M., Yazdani, Y.   +3 more
core  

Differential Tissue Response to Growth Hormone in Mice [PDF]

, 2018
Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R., Berry, Ryan, Frank, Stuart J., McGinnis, Graham R., Young, Martin E.   +4 more
core   +2 more sources

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

Advanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo   +15 more
wiley   +1 more source

Integrated dentin caries treatment with application of preparations from brown algae and low-frequency laser radiation

Эндодонтия Today, 2020
The complex technique of treatment of caries of a dentine with application of a preparation from brown seaweed and the low-intensive laser is presented in article.

doaj  

Effects of heme oxygenase isozymes on Leydig cells steroidogenesis [PDF]

, 2009
In the present study, we demonstrate the expression of heme oxygenase (HO) isozymes, HO-1 and HO-2 (listed as HMOX1 and HMOX2 in the MGI Database), in MA-10 Leydig tumor cells and its effect on steroidogenesis. The well-known HO inducer, hemin, increased
Besio Moreno, Marcos Alberto, Cymeryng, Cora Betriz, Monzón, Casandra Margarita, Pagotto, Romina María del Luján, Pignataro, Omar Pedro, Piotrkowski, Barbara, Reche, Cecilia   +6 more
core   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source