Results 181 to 190 of about 149,082 (291)

Regional corneal biomechanics assessment as a function of age using Strain–Stress Index maps

open access: yesOphthalmic and Physiological Optics, EarlyView.
Abstract Purpose To gain a better understanding of corneal Stress–Strain Index (SSI) maps in healthy eyes and to determine their changes with age. Method The eyes of 72 participants (age 43.1 ± 20.9 years, 69.5% female) were included in the analysis, considering the left and right eyes separately.
Vahoura Tahsini   +6 more
wiley   +1 more source

Reduced quality of life in corneal dystrophy - a prospective case control study. [PDF]

open access: yesBMC Ophthalmol
Elhardt C   +5 more
europepmc   +1 more source

High yield production of the antifungal proteins PeAfpA and PdAfpB by vacuole targeting in a TMV‐based expression vector

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Antifungal proteins (AFPs) derived from filamentous fungi show great potential against economically significant fungi that cause plant diseases and consequently threat food safety and security. This study focuses on the Penicillium expansum PeAfpA and Penicillium digitatum PdAfpB proteins and their activity against several phytopathogens.
Adrià Bugeda   +6 more
wiley   +1 more source

Characterisation of Early Biosynthetic Steps of Atractylon via an Integrative Strategy

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Atractylodes lancea, a vital medicinal plant, is renowned for its bioactive sesquiterpenoids, particularly atractylon. Despite its therapeutic importance, the genetic and biosynthetic pathways underlying atractylon production remain insufficiently understood.
Juan Zhu   +12 more
wiley   +1 more source

Benzoxazole Derivatives as Potent FXR and PPARα Dual Agonists With Anti‐Fibrotic and Metabolic Regulatory Effects [PDF]

open access: yesMedComm (2020)
MHY5396, a benzoxazole derivative, functions as a potent dual FXR and PPARα agonist. It exhibits significant anti‐fibrotic and metabolic regulatory effects, effectively improving liver and kidney fibrosis in experimental models. These findings highlight its potential as a therapeutic candidate for fibrosis and metabolic disorders.
Kim M   +15 more
europepmc   +2 more sources

The type 1 diabetes candidate genes PTPN2 and BACH2 regulate the IFN-α-induced crosstalk between JAK/STAT and MAPKs pathways in human beta cells. [PDF]

open access: yesEBioMedicine
Roca-Rivada A   +12 more
europepmc   +1 more source

Natural Variation of a PPR Coding Gene SST1 Confers Salt Tolerance During Soybean Domestication

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Soil salinity is one of the constraints that adversely affect seedling growth and limit soybean yield. Identifying salt tolerance genes and profiling their allele variants are crucial for elucidating the mechanisms underlying salt tolerance in soybean and enabling the genetic improvement of salt‐tolerant cultivars.
Hui Wang   +14 more
wiley   +1 more source

TRAF6 integrates innate immune signals to regulate glucose homeostasis via Parkin-dependent and Parkin-independent mitophagy. [PDF]

open access: yesSci Adv
Levi-D'Ancona E   +17 more
europepmc   +1 more source

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