The Cell-Cycle Regulatory Protein p21CIP1/WAF1 Is Required for Cytolethal Distending Toxin (Cdt)-Induced Apoptosis. [PDF]
, 2020 The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) induces lymphocytes to undergo cell-cycle arrest and apoptosis; toxicity is dependent upon the active Cdt subunit, CdtB.
Boesze-Battaglia, Kathleen +4 more
core +2 more sources
Computed tomography-osteoabsorptiometry for assessing the density distribution of subchondral bone as a measure of long-term mechanical adaptation in individual joints [PDF]
, 1989 To estimate subchondral mineralisation patterns which represent the long-term loading history of individual joints, a method has been developed employing computed tomography (CT) which permits repeated examination of living joints.
A Schleicher +23 more
core +1 more source
Characteristics of the elderly in high - resolution computed tomography lung densitometry [PDF]
, 2004 To determine the characteristics of the elderly in high - resolution computed tomography (HRCT) lung densitometry, mean lung density (MLD) and relative area of the lungs showing attenuation values less than -950 HU (RA(950)) on HRCT were evaluated in ...
Ashida, Kozo +9 more
core +1 more source
Health professionals, their medical interventions and uncertainty : a study focusing on women at midlife [PDF]
, 2005 Health professionals face a tension between focusing on the individual and attending to health issues for the population as a whole. This tension is intrinsic to medicine and gives rise to medical uncertainty, which here is explored through accounts of ...
Alaszewski +48 more
core +1 more source
Computed tomography-osteoaboorptiometry [PDF]
, 1990 A method of making a visual display of subchondral mineralization in the major synovial joints is described. Unlike existing procedures, it can be used on the living subject. A modified application of computed tomography-densitometry, computed tomography-
Hodapp, Norbert +4 more
core +1 more source
NRF2 regulates HER1 signaling pathway to modulate the sensitivity of ovarian cancer cells to lapatinib and erlotinib [PDF]
, 2017 NF-E2-related factor 2 (NRF2) regulates the transcription of a battery of metabolic and cytoprotective genes. NRF2 and epidermal growth factor receptors (EGFRs/HERs) are regulators of cellular proliferation and determinants of cancer initiation and ...
Bown, James L. +5 more
core +5 more sources
Weak Gravitational Lensing by Voids [PDF]
, 1998 We consider the prospects for detecting weak gravitational lensing by underdensities (voids) in the large-scale matter distribution. We derive the basic expressions for magnification and distortion by spherical voids. Clustering of the background sources
Amendola, Luca +2 more
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Dynamin- and Rab5-Dependent Endocytosis of a Ca2+-Activated K+ Channel, KCa2.3 [PDF]
, 2012 Regulation of the number of ion channels at the plasma membrane is a critical component of the physiological response. We recently demonstrated that the Ca2+-activated K+ channel, KCa2.3 is rapidly endocytosed and enters a Rab35- and EPI64C-dependent ...
Agustin Guerrero-Hernandez +5 more
core +9 more sources
Amalgamated reference data for size-adjusted bone densitometry measurements in 3598 children and young adults – the ALPHABET study [PDF]
, 2016 The increasing use of dual energy X-ray absorptiometry (DXA) in children has led to the need for robust reference data for interpretation of scans in daily clinical practice.
Adams, J.E. +12 more
core +5 more sources
Effect of corneal light scatter on vision: a review of the literature [PDF]
, 2016 The cornea is the transparent connective tissue window at the front of the eye. The physiological role of the cornea is to conduct external light into the eye, focus it, together with the lens, onto the retina, and to provide rigidity to the entire ...
MARAONE, GIORGIA +4 more
core +3 more sources