Results 41 to 50 of about 170,031 (283)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Proceedings of the Research Conference with International Participation «Musculoskeletal System: from Childhood to Old Age» (Donetsk, 27–29 November 2013)

open access: yesBolʹ, Sustavy, Pozvonočnik, 2013
The theses of the research conference with international participation “Musculoskeletal system: from childhood to old age”, that took place in Donetsk (Ukraine) in 27 – 29 November, 2016) are presented.
K.N. Valiyeva   +2 more
doaj   +1 more source

TLC-densitometric analysis of allantoin in Symphytum officinale L. roots

open access: yesActa Pharmaceutica, 2020
A TLC-densitometric method for determination of allantoin in Symphytum officinale root was developed. Densitometric quantification of allantoin was carried out on TLC Si60 plates with butanol-50 % methanol/formic acid, 66.5:33.2:0.3 (V/V/V) as developing
Kimel Katarzyna   +3 more
doaj   +1 more source

FRAX® International Task Force of the 2010 Joint International Society for Clinical Densitometry andamp; International Osteoporosis Foundation Position Development Conference

open access: yes, 2011
Osteoporosis is a serious worldwide epidemic. FRAX® is a web-based tool developed by the Sheffield WHO Collaborating Center team, that integrates clinical risk factors and femoral neck BMD and calculates the 10 year fracture probability in order to help ...
Cauley J.A.   +2 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Application of targeted 2D planar chromatography in the control of ginkgolic acids in some herbal drugs and dietary supplements

open access: yesActa Pharmaceutica, 2020
Two-step targeted 2D planar chromatographic method (2DTLC) was used in the determination of ginkgolic acids in pharmaceuticals and dietary supplements.
Migas Piotr   +3 more
doaj   +1 more source

Quantitative Analysis for Lung Disease on Thin-Section CT

open access: yesDiagnostics, 2023
Thin-section computed tomography (CT) is widely employed not only for assessing morphology but also for evaluating respiratory function. Three-dimensional images obtained from thin-section CT provide precise measurements of lung, airway, and vessel ...
Tae Iwasawa   +4 more
doaj   +1 more source

Bone densitometry for the assessment of osteoporosis [PDF]

open access: yes, 2010
The primary clinical role of the non-invasive\ud physical measurement of a bone, generally\ud referred to as ‘bone densitometry,’ is to identify\ud those subjects at risk of an osteoporotic fracture\ud and their subsequent response to pharmaceutical\ud ...
Langton, Christian M.
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Bone Densitometry in Children

open access: yesSeminars in Musculoskeletal Radiology, 2014
Maximizing peak bone mass in childhood is relevant to optimizing bone health in later life, so the study of the skeleton in children in health and disease is important. Dual-energy X-ray absorptiometry (DXA) is the most widely used clinical tool for the assessment of bone status in children.
openaire   +3 more sources

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