Results 61 to 70 of about 248,416 (349)
Melt densities in the Na2O-FeO-Fe2O3-SiO2 system and the partial molar volume of tetrahedrally-coordinated ferric iron in silicate melts [PDF]
, 1988 The densities of 12 melts in the Na2O-FeO-Fe2O3-SiO2 system have been determined in equilibrium with air, in the temperature range of 1000–1500°C, using the double bob, Archimedean technique.
Brearley, Mark +2 more
core +1 more source
Seminars in Musculoskeletal Radiology, 2014 Maximizing peak bone mass in childhood is relevant to optimizing bone health in later life, so the study of the skeleton in children in health and disease is important. Dual-energy X-ray absorptiometry (DXA) is the most widely used clinical tool for the assessment of bone status in children.
openaire +3 more sources
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Estrogens promote misfolded proinsulin degradation to protect insulin production and delay diabetes [PDF]
, 2018 Summary: Conjugated estrogens (CE) delay the onset of type 2 diabetes (T2D) in postmenopausal women, but the mechanism is unclear. In T2D, the endoplasmic reticulum (ER) fails to promote proinsulin folding and, in failing to do so, promotes ER stress and
Allard, Camille +12 more
core +2 more sources
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Molecular Genetics and Metabolism ReportsObjectives: Phenylketonuria is a hereditary condition caused by the deficiency of the enzyme phenylalanine hydroxylase, leading to abnormal phenylalanine metabolism.
Akram Ehsasat Vatan, M.D. +3 more
doaj +1 more source
CLINICAL CASE OF RARE TYPE V OSTEOGENESIS IMPERFECTA
Педиатрическая фармакология, 2015 Osteogenesis imperfecta, also known as the brittle bone disease, is a clinically heterogenic hereditary connective tissue disease characterized by brittle bones and high risk of skeletal bone fractures.
G. T. Yakhyayeva +8 more
doaj +1 more source
Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells [PDF]
, 2018 Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression.
Acconcia +111 more
core +2 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner. [PDF]
, 2018 The tumor promoter 12-O-tetra-decanoylphorbol-13-acetate (TPA) has been defined by its ability to promote tumorigenesis on carcinogen-initiated mouse skin.
Carson, Dennis A +12 more
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