Results 71 to 80 of about 248,416 (349)

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Utilization of bone densitometry for prediction and administration of bisphosphonates to prevent osteoporosis in patients with prostate cancer without bone metastases receiving antiandrogen therapy

Cancer Management and Research, 2014
Abby Holt,1 Muhammad A Khan,2 Swetha Gujja,3 Rangaswmy Govindarajan31Arkansas Department of Health, Little Rock, 2White River Health System, Batesville, 3Division of Hematology/Oncology, University of Arkansas for Medical Sciences, Little Rock, AR ...
Holt A, Khan MA, Gujja S, Govindarajan R
doaj  

Dual energy X-ray absorptiometry diagnostic discordance between Z scores and T scores in a young Iranian population [PDF]

, 2014
Background: Dual-energy X-ray Absorptiometry (DXA) is considered the gold standard for non-invasive measurement of bone mass. T-scores and Z-scores are used to present the results of bone mass. The present study was designed to evaluate the discordance
Heidari, Benham, Khashayar, Patricia, Larijani, Bagher, Pajouhi, Atieh, Rezaei Homami, Mohsen, Soltani, Akbar   +5 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Measuring of Mandible Bone Density in Dogs Using /Digital Radiography/ Radiovisigraphy

Acta Veterinaria, 2020
Radiological diagnostics serves as one of the basic monitoring techniques in veterinary dental practice. The recent up-to-date literature data based on the findings of digital radiology/radiovisiography (RVG) in general dentistry inspired the authors to ...
Ilić Dragan, Stojanović Ljiljana, Antonijević Djordje, Milutinović-Smiljanić Sanja, Savić-Stanković Tatjana, Milosavljević Željko   +5 more
doaj   +1 more source

Correlation Between Low Bone Density and Disease Activity in Patients with Ulcerative Colitis [PDF]

, 2015
BACKGROUND Different clinical and epidemiological studies using dual-energy X-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.
Aghaei, M., Amiriani, T., Besharat, M., Besharat, S., Faghani, M., Joshaghani, H., Mirkarimi, H.S., Pourramezan, Z., Roshandel, G.   +8 more
core  

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Investigation of How Corneal Densitometry Artefacts Affect the Imaging of Normal and Keratoconic Corneas

Bioengineering
Purpose: To investigate corneal densitometry artefacts found in Pentacam Scheimpflug scans and their potential effect on assessing keratoconic (KC) corneas compared to normal (N) corneas.
Rami Alanazi, Louise Pellegrino Gomes Esporcatte, Lynn White, Marcella Q. Salomão, Bernardo T. Lopes, Renato Ambrósio Jr., Ahmed Abass   +6 more
doaj   +1 more source

ASSESSMENT OF BONE MINERAL DENSITY IN PATIENTS WITH HODGKIN’S LYMPHOMA

Сибирский научный медицинский журнал, 2019
Currently, Hodgkin’s lymphoma (HL) is considered as a potentially curable disease. The polychemotherapy including various combinations of cytostatic drugs and glucocorticoids appears the standard of treatment in patients with HL.
M. S. Voytko, T. I. Pospelova, V. V. Klimontov, O. N. Fazullina, E. V. Mezit   +4 more
doaj   +1 more source