Results 91 to 100 of about 9,598,281 (302)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

One-step formation of three-dimensional interconnected T-shaped microstructures inside composites by orthogonal bidirectional self-assembly method

open access: yesScience and Technology of Advanced Materials
The fillers inside a polymer matrix should typically be self-assembled in both the horizontal and vertical directions to obtain 3-dimentional (3D) percolation pathways, whereby the fields of application can be expanded and the properties of organic ...
Zhiming Shen   +5 more
doaj   +1 more source

Spiral Density Waves in M81. I. Stellar Spiral Density Waves

open access: yes, 2014
Aside from the grand-design stellar spirals appearing in the disk of M81, a pair of stellar spiral arms situated well inside the bright bulge of M81 has been recently discovered by Kendall et al. (2008).
Feng, Chien-Chang   +3 more
core   +1 more source

q-Density points and q-density topologies

open access: yesTopology and its Applications, 2012
Let \(\lambda (.)\) denote the Lebesgue measure and \(\Omega \) the \(\sigma \) -algebra of Lebesgue measurable subsets of \(\mathbb R\). of real numbers. For \( n\geq 1\), \(x\in \mathbb R\) and \(A\in \Omega \), define the sets \(A_{n}(x)=\left[ n(A-x\right] \cap \left[ -1,1\right] \) and \(A_{n}^{\prime }(x)=\left[ -1,1 \right] \smallsetminus A_{n ...
Papachristodoulos, C.   +1 more
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Self-Driven Cycle and Thermal Characteristics of Seawater Battery System with a Preheater

open access: yesEnergies
As a novel energy storage technology, seawater batteries exhibit significant application potential across various domains, including marine exploration, underwater communication, and island power supply.
Haihong Dong   +6 more
doaj   +1 more source

Are exposures to ready-to-eat food environments associated with type 2 diabetes? A cross-sectional study of 347 551 UK Biobank adult participants

open access: yesThe Lancet Planetary Health, 2018
Summary: Background: Rapid urbanisation and associated socioeconomic transformations have modified current lifestyles, shifting dietary preferences towards ready-to-eat, calorie-dense food of poor nutritional quality.
Chinmoy Sarkar, PhD   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Associations of heat exposure with mental health and suicide in children and adolescents: a systematic review and meta-analysis

open access: yesnpj Mental Health Research
Limited evidence exists on the association between high temperature and mental health in younger age group. We conducted a systematic search on PubMed, Web of Science, CINAHL Plus and PsycInfo and reviewed studies that explore the associations of heat ...
Ka Yan Lai   +2 more
doaj   +1 more source

Effects of Aging and Dual-Task Demands on the Comprehension of Less Expected Sentence Continuations: Evidence From Pupillometry

open access: yesFrontiers in Psychology, 2019
Prior studies on language processing in aging have shown that older adults experience integration difficulties for contextually unpredictable target words (as indicated by low cloze probabilities in prior ratings), and that such comprehension ...
Katja I. Häuser   +5 more
doaj   +1 more source

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