Results 101 to 110 of about 5,780,309 (303)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Multivariate Density Estimation and Visualization [PDF]

This chapter examines the use of flexible methods to approximate an unknown density function, and techniques appropriate for visualization of densities in up to four dimensions. The statistical analysis of data is a multilayered endeavor.
Scott, David W.
core  

Energy loss of an energetic Ga ion in hot Au plasmas

Matter and Radiation at Extremes, 2016
Self-consistent calculations of energy loss for a Ga ion moving in hot Au plasmas are made under the assumption of wide ranges of the projectile energy and the plasma temperature with all important mechanisms considered in detail.
Bin He, Xujun Meng, Jianguo Wang
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Evaluating the Environmental Implications of Density: a comparative case study on the relationship between density, urban block typology and sky view factor performance

, 2010
This study explores the relationship between density, built form typologies and their respective environmental quality in terms of Sky View Factor (SVF) distribution on both the facade and ground levels by examining representative residential precincts ...
P. Janssen, L. Malone-Lee, D. Hii, J. Zhang, B. Tan, C. Heng   +5 more
core  

Control Strategy for Hybrid Magnetic Bearing Based on Improved Cascaded Reduced-Order Active Disturbance Rejection Controller

CES Transactions on Electrical Machines and Systems
During the startup of the hydraulic turbine generators, the hybrid magnetic bearing support system exhibits displacement fluctuations, and the nonlinearity and strong coupling characteristics of the magnetic bearings limit the accuracy of rotor modeling,
Kaiyu Shan, Ke Wang, Wei Zhang, Yuxiang Zhu, Lu Zhao, Jinquan Zhu   +5 more
doaj   +1 more source

Causal Effect of Leading-Edge Sawtooth Configuration on Flow Field Characteristics and Aerodynamic Losses in the Supersonic Compressor Cascade [PDF]

Journal of Applied Fluid Mechanics
This study focuses on the TM-141 supersonic compressor blade as the subject of investigation. Utilizing the Reynolds-averaged numerical simulation approach, the study examines the impact of the leading-edge sawtooth structure on the blade grid, flow ...
S. J. Hu, Z. J. Wei, M. Ni, G. M. Ren
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Default priors for density estimation with mixture models [PDF]

, 2010
The infinite mixture of normals model has become a popular method for density estimation problems. This paper proposes an alternative hierarchical model that leads to hyperparameters that can be interpreted as the location, scale and smoothness of the ...
Griffin, Jim E.
core   +1 more source

Coupling Model and Early-Stage Internal Short Circuits Fault Diagnosis for Gel Electrolyte Lithium-Ion Batteries

Batteries
This paper presents a method for modeling and predicting ISC in gel-electrolyte lithium-ion batteries, addressing critical safety concerns in electric vehicles.
Liye Wang, Jinlong Wu, Chunxiao Ma, Xianzhong Sun, Lifang Wang, Chenglin Liao   +5 more
doaj   +1 more source