Results 121 to 130 of about 5,780,309 (303)
Nonparametric Density Estimation for Positive Time Series [PDF]
The Gaussian kernel density estimator is known to have substantial problems for bounded random variables with high density at the boundaries. For i.i.d. data several solutions have been put forward to solve this boundary problem. In this paper we propose
Jeroen V.K. Rombouts, Taoufik Bouezmarni
core
mSystemsThe major oral odor compound methyl mercaptan (CH3SH) is strongly associated with halitosis and periodontitis. CH3SH production stems from the metabolism of polymicrobial communities in periodontal pockets and on the tongue dorsum. However, understanding
Takeshi Hara +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Discover Mechanical EngineeringThis paper presents the development and metrological validation of an automated 2-axis mass transfer system designed for the high-precision calibration of standards ranging from 2 to 50 kg.
B. M. Sayed +2 more
doaj +1 more source
EnergiesIn order to improve the output torque/current utilization of five-phase interior permanent magnet synchronous motor (FP-IPMSM) when running below base speed, a multi-dimensional maximum torque per ampere (MTPA) control strategy based on virtual signal ...
Yihong Qin +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Density-Corrected Density Functional Theory for Molecular Properties
Density-corrected (DC) density functional theory (DFT) has been proposed to overcome difficulties related to the self-interaction error. The procedure uses the Hartree–Fock electron density (matrix) non-self-consistently in conjunction with an ...
Jochen Autschbach (407917) +1 more
core +1 more source
, 2017 R code that takes the data from the varying parasite density experiment and integrates with the other R code files to fit the models, make the AIC table, and make the parameter ...
Flaxman, Samuel +11 more
core +1 more source
Communications MedicineBackground Acute health effects of temperature extremes and variability in temperate zones has been rarely quantified. We examine the associations of ambient temperature and temperature change between neighbouring days with all-cause and cause-specific ...
Ka Yan Lai +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source