Results 121 to 130 of about 9,598,281 (302)

Dielectric Breakdown Characteristics of Biaxially Oriented Polypropylene Films: Surface Structures on Thickness Dependence

High Voltage
Film capacitors, essential for energy storage in power systems, benefit from reduced film thickness to increase capacitance and lower costs. While the inverse power law traditionally links higher electric strength with thinner films, its validity ...
Chuansheng Zhang, Chengyan Ren, Yu Feng, Yi Luo, Cheng Zhang, Tao Shao   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Research on Multi-Dimensional MTPA Control for Five-Phase Interior Permanent Magnet Synchronous Motor

Energies
In order to improve the output torque/current utilization of five-phase interior permanent magnet synchronous motor (FP-IPMSM) when running below base speed, a multi-dimensional maximum torque per ampere (MTPA) control strategy based on virtual signal ...
Yihong Qin, Peng Zhou, Zhibao Yuan, Haiping Xu   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Design control and investigation of a two axis robotic platform for high precision fifty kilogram mass calibration

Discover Mechanical Engineering
This paper presents the development and metrological validation of an automated 2-axis mass transfer system designed for the high-precision calibration of standards ranging from 2 to 50 kg.
B. M. Sayed, Omar Zahra, Alaaeldin A. Eltawil   +2 more
doaj   +1 more source

Interspecies metabolite transfer fuels the methionine metabolism of Fusobacterium nucleatum to stimulate volatile methyl mercaptan production

mSystems
The major oral odor compound methyl mercaptan (CH3SH) is strongly associated with halitosis and periodontitis. CH3SH production stems from the metabolism of polymicrobial communities in periodontal pockets and on the tongue dorsum. However, understanding
Takeshi Hara, Akito Sakanaka, Richard J. Lamont, Atsuo Amano, Masae Kuboniwa   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Ambient temperature and the variability between neighbouring days impacts in-patient hospitalizations in the United Kingdom

Communications Medicine
Background Acute health effects of temperature extremes and variability in temperate zones has been rarely quantified. We examine the associations of ambient temperature and temperature change between neighbouring days with all-cause and cause-specific ...
Ka Yan Lai, Chris Webster, John Gallacher, Chinmoy Sarkar   +3 more
doaj   +1 more source