Results 111 to 120 of about 9,598,281 (302)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Control Strategy for Hybrid Magnetic Bearing Based on Improved Cascaded Reduced-Order Active Disturbance Rejection Controller

CES Transactions on Electrical Machines and Systems
During the startup of the hydraulic turbine generators, the hybrid magnetic bearing support system exhibits displacement fluctuations, and the nonlinearity and strong coupling characteristics of the magnetic bearings limit the accuracy of rotor modeling,
Kaiyu Shan, Ke Wang, Wei Zhang, Yuxiang Zhu, Lu Zhao, Jinquan Zhu   +5 more
doaj   +1 more source

On Holographic Entanglement Density

, 2017
We use holographic duality to study the entanglement entropy (EE) of Conformal Field Theories (CFTs) in various spacetime dimensions $d$, in the presence of various deformations: a relevant Lorentz scalar operator with constant source, a temperature $T$,
Gushterov, Nikola I., O'Bannon, Andy, Rodgers, Ronnie   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Coupling Model and Early-Stage Internal Short Circuits Fault Diagnosis for Gel Electrolyte Lithium-Ion Batteries

Batteries
This paper presents a method for modeling and predicting ISC in gel-electrolyte lithium-ion batteries, addressing critical safety concerns in electric vehicles.
Liye Wang, Jinlong Wu, Chunxiao Ma, Xianzhong Sun, Lifang Wang, Chenglin Liao   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Quasi-concave density estimation

, 2010
Maximum likelihood estimation of a log-concave probability density is formulated as a convex optimization problem and shown to have an equivalent dual formulation as a constrained maximum Shannon entropy problem.
Koenker, Roger, Mizera, Ivan
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Low Density Lattice Codes

, 2007
Low density lattice codes (LDLC) are novel lattice codes that can be decoded efficiently and approach the capacity of the additive white Gaussian noise (AWGN) channel.
Meir Feder, Naftali Sommer, Ofir Shalvi, Senior Member   +3 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source