Results 101 to 110 of about 1,733,991 (287)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Density estimation via binless multidimensional integration

Machine Learning: Science and Technology
We introduce the binless multidimensional thermodynamic integration (BMTI) method for nonparametric, robust, and data-efficient density estimation.
Matteo Carli, Alex Rodriguez, Alessandro Laio, Aldo Glielmo   +3 more
doaj   +1 more source

Local Vehicle Density Estimation on Highways Using Awareness Messages and Broadcast Reliability of Vehicular Communications

Vehicles
This paper presents a novel method for locally estimating vehicle density on highways based on vehicle-to-vehicle (V2V) communication, a communication mode within intelligent transport systems (ITSs), enabled via IEEE 802.11p and 3GPP C-V2X technologies.
Zhijuan Li, Xintong Wu, Zhuofei Wu, Jing Zhao, Xiaomin Ma, Alessandro Bazzi   +5 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Estimation of Probability Density

The Annals of Mathematical Statistics, 1965
Assuming that the distribution being sampled is absolutely continous, Parzen [3] has established the consistency and asymptotic normality of a class of estimators $\{f_n(x)\}$ based on a random sample of size $n$, for estimating the probability density.
openaire   +2 more sources

Lp adaptive density estimation

Bernoulli, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kerkyacharian, Gérard, Picard, Dominique, Tribouley, Karine   +2 more
openaire   +3 more sources

Estimation of subgraph density in noisy networks

, 2020
While it is common practice in applied network analysis to report various standard network summary statistics, these numbers are rarely accompanied by uncertainty quantification.
Chang, Jinyuan, Kolaczyk, Eric D., Yao, Qiwei   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

EMSPAN: Efficient Multi-Scale Pyramid Attention Network for Object Counting Under Size Heterogeneity and Dense Scenarios

IEEE Access
Computer vision is becoming an increasingly vital field, offering significant opportunities for real-world applications. Object counting is one of its core aspects, with increasing utilization across scientific fields involving objects of varying sizes ...
Phu Nguyen Phan Hai, Bao Bui Quoc, Trang Hoang   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source