Results 51 to 60 of about 2,140 (251)

Synthesis, antimicrobial evaluation, molecular docking, and drug-likeness assessment of novel phenothiazine chromene hybrid compounds

open access: yesScientific Reports
By carefully hybridizing with scaffolds generated from chromene, pyranochromene, and cyanoacetamide, a novel class of phenothiazine-based heterocycles was created.
Nesma M. Bayoumy   +3 more
doaj   +1 more source

Knowledge, Attitude, and Practice of Biosafety Guidelines among Dental Undergraduates during COVID-19 Pandemic at a Dental Institution in North Karnataka – An Institution-Based Cross-Sectional Study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology
Background: Coronavirus Disease 2019 (COVID-19) pandemic had universally affected every field of health sciences with dentistry being no exception. The current study was planned to assess the preparedness of dental undergraduates to deal with patients ...
Vaishnavi A. Nidarkar   +5 more
doaj   +1 more source

Real‐Time Holographic Feedback via Mixed Reality Sensorized Laryngoscope Training System Enhances Pediatric Intubation Training

open access: yesAdvanced Robotics Research, EarlyView.
We proposed a Mixed Reality Sensorized Laryngoscope Training System to provide real‐time holographic torque feedback during pediatric endotracheal intubation simulation. Visualization formats are evaluated to reduce tracking error and visual demand.
Jiaqi Li   +5 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

open access: yesAdvanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu   +17 more
wiley   +1 more source

Design, synthesis, molecular docking and cytotoxic evaluation of novel pyrimidine-based sulfonamide derivatives as potent anticancer agents: SAR insights and biological profiling

open access: yesScientific Reports
The low selectivity and significant toxicity of current chemotherapeutic medicines make the research and development of novel anticancer agents an urgent necessity.
Nesma M. Bayoumy   +3 more
doaj   +1 more source

Class II subdivision correction with clear aligners using intermaxilary elastics

open access: yesProgress in Orthodontics, 2018
Background To describe an esthetic orthodontic treatment using aligners in an adult patient with class II subdivision associated with crowding and dental crossbite.
Luca Lombardo   +4 more
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

open access: yesAdvanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait   +7 more
wiley   +1 more source

Dental Fear and Anxiety in Children and Adolescents: Qualitative Study Using YouTube

open access: yesJournal of Medical Internet Research, 2013
BackgroundDental fear and anxiety (DFA) refers to the fear of and anxiety towards going to the dentist. It exists in a considerable proportion of children and adolescents and is a major dilemma in pediatric dental practice.
Gao, Xiaoli   +4 more
doaj   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

open access: yesAdvanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li   +9 more
wiley   +1 more source

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