Results 51 to 60 of about 1,981 (251)

Synthesis, antimicrobial evaluation, molecular docking, and drug-likeness assessment of novel phenothiazine chromene hybrid compounds

Scientific Reports
By carefully hybridizing with scaffolds generated from chromene, pyranochromene, and cyanoacetamide, a novel class of phenothiazine-based heterocycles was created.
Nesma M. Bayoumy, Ahmed A. Fadda, Hatem E. Gaffer, Nanees N. Soliman   +3 more
doaj   +1 more source

Knowledge, Attitude, and Practice of Biosafety Guidelines among Dental Undergraduates during COVID-19 Pandemic at a Dental Institution in North Karnataka – An Institution-Based Cross-Sectional Study

Journal of Indian Academy of Oral Medicine and Radiology
Background: Coronavirus Disease 2019 (COVID-19) pandemic had universally affected every field of health sciences with dentistry being no exception. The current study was planned to assess the preparedness of dental undergraduates to deal with patients ...
Vaishnavi A. Nidarkar, Zameera Naik, S Lokesh Kumar, Anand Badavannavar, Muskan D. Hinduja, Ram Surath Kumar   +5 more
doaj   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Knowledge of dentists, dental auxiliaries, and students regarding the COVID-19 pandemic in Saudi Arabia: A Cross-Sectional Survey [PDF]

BMC Oral Health, 2020
Shahin S, Bugshan A, Almulhim K, AlSharief M, Al-Dulaijan Y, al-Qarni F.   +5 more
europepmc   +2 more sources

Design, synthesis, molecular docking and cytotoxic evaluation of novel pyrimidine-based sulfonamide derivatives as potent anticancer agents: SAR insights and biological profiling

Scientific Reports
The low selectivity and significant toxicity of current chemotherapeutic medicines make the research and development of novel anticancer agents an urgent necessity.
Nesma M. Bayoumy, Ahmed A. Fadda, Hatem E. Gaffer, Nanees N. Soliman   +3 more
doaj   +1 more source

Class II subdivision correction with clear aligners using intermaxilary elastics

Progress in Orthodontics, 2018
Background To describe an esthetic orthodontic treatment using aligners in an adult patient with class II subdivision associated with crowding and dental crossbite.
Luca Lombardo, Anna Colonna, Antonella Carlucci, Teresa Oliverio, Giuseppe Siciliani   +4 more
doaj   +1 more source

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source

Dental Fear and Anxiety in Children and Adolescents: Qualitative Study Using YouTube

Journal of Medical Internet Research, 2013
BackgroundDental fear and anxiety (DFA) refers to the fear of and anxiety towards going to the dentist. It exists in a considerable proportion of children and adolescents and is a major dilemma in pediatric dental practice.
Gao, Xiaoli, Hamzah, SH, Yiu, Cynthia Kar Yung, McGrath, Colman, King, Nigel M   +4 more
doaj   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source