Results 111 to 120 of about 17,874 (251)

Interleukin Expression and Activation of Inflammatory/Apoptosis Pathways on Human Gingival Fibroblasts Exposed to Light-Cured Dental Composites. [PDF]

Polymers (Basel)
Sorrentino E, D'Arcangelo C, Mazzone A, Fonticoli L, Frisone A, Coppola L, Mazzon E, Trubiani O, Pizzicannella J, Marconi GD, Diomede F, De Angelis F.   +11 more
europepmc   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

Multidimensional Characterization of Surface Properties and Microbial Biofilm Formation in Commercial Flowable Resin-Based Dental Composites. [PDF]

J Funct Biomater
Floare L, Bolos OC, Dumitrescu R, Caraba MN, Petculescu IM, Opris C, Balean O, Bolchis V, Todor BI, Savencu CE, Galuscan A, Jumanca D.   +11 more
europepmc   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

In Vitro Evaluation of Cytotoxicity in Novel Nano-Filled Bulk-Fill Flowable Dental Composites. [PDF]

Rwanda J Med Health Sci
Shreshtha M, Pradeep S, Dona S, Priscilla ASD, Sambandam V.   +4 more
europepmc   +1 more source

Effects of Novel Dental Composites on Streptococcus mutans Biofilms. [PDF]

J Funct Biomater, 2023
Yaghmoor RB, Abdel-Hadi M, Petridis H, Allan E, Young AM.   +4 more
europepmc   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

Impact of Functionalized Graphene Nanoplatelet Incorporation on the Properties of 3D-Printed Resin-Based Dental Composites. [PDF]

ACS Omega
Beltrami LVR, Goulart MEP, Frassini R, Roesch Ely M, de Oliveira Gamba T, Piazza D, Zattera AJ.   +6 more
europepmc   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

Advanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng, Jaegeon Joo, Yu Meng Li, Cheng Ji Li, Ali Taghizadeh, Seung Jae Shin, Buuvee Bayarkhangai, Tae‐Woo Ha, Sak Lee, Jaewoo Chung, Bo‐Eun Yoon, Hye Sung Kim, Inkyung Jung, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +15 more
wiley   +1 more source

Bonding Performance, Mass Stability and Mechanical Properties of Self-Adhesive Resin Composites and Conventional Dental Composites: A Comparative Laboratory Evaluation. [PDF]

Polymers (Basel)
Islam MS, Padmanabhan V, Wahbeh NF, Almaghribi LY, Hashim NT, Aryal A C S, Guha U, Rahman MM.   +7 more
europepmc   +1 more source