Results 201 to 210 of about 2,334,932 (249)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

open access: yesInterdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao   +6 more
wiley   +1 more source

Continuous local minocycline delivery from PLA nanosphere-coated dental implants with long-term antibacterial activity and biocompatibility. [PDF]

open access: yesRSC Adv
Patiyananuwat N   +6 more
europepmc   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez   +6 more
wiley   +1 more source

Is bruxism associated with the use of screen devices in children and adolescents? A systematic review. [PDF]

open access: yesBraz Oral Res
Shqair AQ   +4 more
europepmc   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice   +8 more
wiley   +1 more source

Comparing Digital Reduction Guides and Free‐Hand Techniques for Predoctoral Crown Preparation Accuracy

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Purpose/Objectives Insufficient tooth reduction compromises crown longevity and aesthetics. This study aimed to determine whether digitally designed, 3D‐printed reduction guides improved crown preparation accuracy and efficiency for dental students compared to freehand preparation.
Xiaoyue Shi, Shuncong Xu, Chenxuan Wei
wiley   +1 more source

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