Results 151 to 160 of about 527,767 (329)
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
, 1989 Spectrum was a newsletter for students, faculty, staff and alumni of the Henry M.
Frankl, Spencer N.
core +1 more source
Advanced Science, EarlyView.Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen +22 more
wiley +1 more source
Analysis of Dental Personnel’s Awareness and Educational Needs Regarding Digital Intraoral Scanners
치위생과학회지Background: As the use of digital intraoral scanners (DIS) has expanded, the demand for digital capabilities is accelerating along with changes in the duties of dental hygienists.
Hye-Jung Kim, Sun-Ju Kim
doaj +1 more source
Advanced Science, EarlyView.TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han +10 more
wiley +1 more source
Regional Action Initiative: Engaging Oregonians in a New Level of Civic Leadership 2008-2013 [PDF]
, 2014 The OCF board of directors launched the Regional Action Initiative (RAI) in 2008 to engage Oregonians in a new level of civic leadership and empower them to improve lives in their regions.
Judy Weller, Juliette Mackin
core
Advanced Science, EarlyView.Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang +9 more
wiley +1 more source
Dental education in Iraq: issues, challenges and future
Journal of Contemporary Medical Sciences, 2017 Medical sciences are the substance for appreciation of prevention and treatment of human diseases and improvement of one’s quality of life. Dentistry on the other hand, is a highly demanding profession that requires standard and evidence-based training ...
Mohammad Hossein Khoshnevisan +3 more
doaj
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Assessing the Utility of Oral and Maxillofacial Surgery Posters as Educational Aids in Dental Education for Undergraduate Students: Is it Useless or Helpful? [PDF]
Seyed Mohammad Ali Seyedi +6 more
openalex +1 more source