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Mechanobiology of Dental Pulp Cells

Cells
The dental pulp is the inner part of the tooth responsible for properly functioning during its lifespan. Apart from the very big biological heterogeneity of dental cells, tooth microenvironments differ a lot in the context of mechanical properties ...
Natalia Bryniarska-Kubiak, Agnieszka Basta-Kaim, Andrzej Kubiak   +2 more
doaj   +3 more sources

Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which were essential for odontoblast differentiation.
Jiahui Fu, Jianfeng Chen, Wenjun Li, Xiaomin Yang, Jingyan Yang, Huixin Quan, Haitao Huang, Gang Chen, Gang Chen   +8 more
openaire   +4 more sources

Inflammation of the Dental Pulp [PDF]

Mediators of Inflammation, 2015
The dental pulp is sensitive to external factors such as microbial infection from dental caries and/or mechanical/chemical irritations during dental procedures. Dental tissue behaves differently to the other connective tissues. It is unique in a way that its soft tissues (pulp and pulp-dentin complex) are enclosed within mineralized hard tissues ...
Park, Sang Hyuk, Ye, Ling, Love, Robert M, Farges, Jean-Christophe, Yumoto, Hiromichi   +4 more
openaire   +5 more sources

Effect of different axial speed patterns on cyclic fatigue resistance of rotary nickel-titanium instruments

BMC Oral Health, 2022
Background To evaluate the effect of pecking motions with faster upward speed on the dynamic cyclic fatigue resistance of nickel-titanium rotary instruments with different metallurgy. Methods Forty each of ProTaper Universal F3 (PTU) and ProTaper Gold F3
Myint Thu, Arata Ebihara, Keiichiro Maki, Miki Nishijo, Shunsuke Kimura, Taro Nakatsukasa, Moe Sandar Kyaw, Takashi Okiji   +7 more
doaj   +1 more source

Microenvironment Influences Odontogenic Mesenchymal Stem Cells Mediated Dental Pulp Regeneration

Frontiers in Physiology, 2021
Dental pulp as a source of nutrition for the whole tooth is vulnerable to trauma and bacterial invasion, which causes irreversible pulpitis and pulp necrosis. Dental pulp regeneration is a valuable method of restoring the viability of the dental pulp and
Xiaoyao Huang, Xiaoyao Huang, Xiaoyao Huang, Zihan Li, Zihan Li, Zihan Li, Anqi Liu, Anqi Liu, Anqi Liu, Xuemei Liu, Xuemei Liu, Xuemei Liu, Hao Guo, Hao Guo, Hao Guo, Meiling Wu, Meiling Wu, Meiling Wu, Xiaoxue Yang, Xiaoxue Yang, Xiaoxue Yang, Bing Han, Bing Han, Bing Han, Kun Xuan, Kun Xuan, Kun Xuan   +26 more
doaj   +1 more source

Phase transformation and mechanical properties of heat-treated nickel-titanium rotary endodontic instruments at room and body temperatures

BMC Oral Health, 2023
Background The aim of this study was to evaluate the phase composition, phase transformation temperatures, bending property, and cyclic fatigue resistance of different heat-treated nickel-titanium (NiTi) rotary instruments with the same tip diameter and ...
Yuka Kasuga, Shunsuke Kimura, Keiichiro Maki, Hayate Unno, Satoshi Omori, Keiko Hirano, Arata Ebihara, Takashi Okiji   +7 more
doaj   +1 more source

Decellularized rat submandibular gland as an alternative scaffold for dental pulp regeneration

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Decellularized extracellular matrix has been recognized as an optimal scaffold for dental pulp regeneration. However, the limited amount of native dental pulp tissue restricts its clinical applications.
Yuanyuan Shi, Yingxin Wang, Zhaochen Shan, Zhenhua Gao   +3 more
doaj   +1 more source

Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9

Scientific Reports, 2022
Accelerated dental pulp mineralization is a common complication in avulsed/luxated teeth, although the mechanisms underlying this remain unclear. We hypothesized that hypoxia due to vascular severance may induce osteo/odontoblast differentiation of ...
Shion Orikasa, Nobuyuki Kawashima, Kento Tazawa, Kentaro Hashimoto, Keisuke Sunada-Nara, Sonoko Noda, Mayuko Fujii, Tetsu Akiyama, Takashi Okiji   +8 more
doaj   +1 more source

Bioactive molecules for regenerative pulp capping [PDF]

European Cells & Materials, 2021
Since the discovery of bioactive molecules sequestered in dentine, researchers have been exploring ways to harness their activities for dental regeneration. One specific area, discussed in this review, is that of dental-pulp capping. Dental-pulp caps are
LLE Whitehouse, NH Thomson, T Do, GA Feichtinger   +3 more
doaj   +1 more source

Periodontal Ligament Cells Are Involved in the Formation of Intracanal Cementum-Like Tissue After Regenerative Endodontic Procedures: A Mouse in situ Model

Frontiers in Dental Medicine, 2022
Regenerative endodontic cell-homing procedures are frequently performed on injured immature teeth diagnosed with pulp necrosis and/or apical periodontitis. The representative histological finding after those procedures is cementum-like tissues filling in
Tomoaki Komada, Keisuke Mitomo, Takatoshi Ikarashi, Masaki Shimono, Han-Sung Jung, Takashi Muramatsu   +5 more
doaj   +1 more source