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Bioprinting of three-dimensional dentin–pulp complex with local differentiation of human dental pulp stem cells [PDF]

open access: yesJournal of Tissue Engineering, 2019
Numerous approaches have been introduced to regenerate artificial dental tissues. However, conventional approaches are limited when producing a construct with three-dimensional patient-specific shapes and compositions of heterogeneous dental tissue.
Jonghyeuk Han   +4 more
doaj   +3 more sources

Local Regeneration of Dentin-Pulp Complex Using Controlled Release of FGF-2 and Naturally Derived Sponge-Like Scaffolds [PDF]

open access: yesInternational Journal of Dentistry, 2012
Restorative and endodontic procedures have been recently developed in an attempt to preserve the vitality of dental pulp after exposure to external stimuli, such as caries infection or traumatic injury.
Chiaki Kitamura   +4 more
doaj   +4 more sources

Microenvironment Influences Odontogenic Mesenchymal Stem Cells Mediated Dental Pulp Regeneration

open access: yesFrontiers in Physiology, 2021
Dental pulp as a source of nutrition for the whole tooth is vulnerable to trauma and bacterial invasion, which causes irreversible pulpitis and pulp necrosis. Dental pulp regeneration is a valuable method of restoring the viability of the dental pulp and
Xiaoyao Huang   +26 more
doaj   +2 more sources

Biomimetic Extracellular Matrix Mediated Somatic Stem Cell Differentiation: Applications in Dental Pulp Tissue Regeneration. [PDF]

open access: yesFrontiers in Physiology, 2015
Dental caries is one of the most widely prevalent infectious diseases in the world. It affects more than half of the world’s population. The current treatment for necrotic dental pulp tissue arising from dental caries is root canal therapy.
Sriram eRavindran, ANNE eGEORGE
doaj   +3 more sources

Extracellular matrix of dental pulp stem cells: Applications in pulp tissue engineering using somatic MSCs [PDF]

open access: yesFrontiers in Physiology, 2014
Dental Caries affects approximately 90% of the world’s population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality.
Sriram eRavindran   +2 more
doaj   +3 more sources

Effect of different axial speed patterns on cyclic fatigue resistance of rotary nickel-titanium instruments

open access: yesBMC Oral Health, 2022
Background To evaluate the effect of pecking motions with faster upward speed on the dynamic cyclic fatigue resistance of nickel-titanium rotary instruments with different metallurgy. Methods Forty each of ProTaper Universal F3 (PTU) and ProTaper Gold F3
Myint Thu   +7 more
doaj   +1 more source

Phase transformation and mechanical properties of heat-treated nickel-titanium rotary endodontic instruments at room and body temperatures

open access: yesBMC Oral Health, 2023
Background The aim of this study was to evaluate the phase composition, phase transformation temperatures, bending property, and cyclic fatigue resistance of different heat-treated nickel-titanium (NiTi) rotary instruments with the same tip diameter and ...
Yuka Kasuga   +7 more
doaj   +1 more source

Decellularized rat submandibular gland as an alternative scaffold for dental pulp regeneration

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Introduction: Decellularized extracellular matrix has been recognized as an optimal scaffold for dental pulp regeneration. However, the limited amount of native dental pulp tissue restricts its clinical applications.
Yuanyuan Shi   +3 more
doaj   +1 more source

Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9

open access: yesScientific Reports, 2022
Accelerated dental pulp mineralization is a common complication in avulsed/luxated teeth, although the mechanisms underlying this remain unclear. We hypothesized that hypoxia due to vascular severance may induce osteo/odontoblast differentiation of ...
Shion Orikasa   +8 more
doaj   +1 more source

Bioactive molecules for regenerative pulp capping [PDF]

open access: yesEuropean Cells & Materials, 2021
Since the discovery of bioactive molecules sequestered in dentine, researchers have been exploring ways to harness their activities for dental regeneration. One specific area, discussed in this review, is that of dental-pulp capping. Dental-pulp caps are
LLE Whitehouse   +3 more
doaj   +1 more source

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