Results 11 to 20 of about 50,485 (167)

Decellularized rat submandibular gland as an alternative scaffold for dental pulp regeneration

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Decellularized extracellular matrix has been recognized as an optimal scaffold for dental pulp regeneration. However, the limited amount of native dental pulp tissue restricts its clinical applications.
Yuanyuan Shi, Yingxin Wang, Zhaochen Shan, Zhenhua Gao   +3 more
doaj   +1 more source

Effect of tip insertion depth and irradiation parameters on the efficacy of cleaning calcium hydroxide from simulated lateral canals using Er:YAG laser- or ultrasonic-activated irrigation

Journal of Dental Sciences, 2021
Background/purpose: Laser-activated root canal irrigation (LAI) with an Er:YAG laser is considered more effective than other irrigation methods, whereas the effectiveness of LAI in cleaning lateral canals far from the laser tip remains unclear.
Yasuhiro Hoshihara, Satoshi Watanabe, Akira Kouno, Kanako Yao, Takashi Okiji   +4 more
doaj   +1 more source

Periodontal Ligament Cells Are Involved in the Formation of Intracanal Cementum-Like Tissue After Regenerative Endodontic Procedures: A Mouse in situ Model

Frontiers in Dental Medicine, 2022
Regenerative endodontic cell-homing procedures are frequently performed on injured immature teeth diagnosed with pulp necrosis and/or apical periodontitis. The representative histological finding after those procedures is cementum-like tissues filling in
Tomoaki Komada, Keisuke Mitomo, Takatoshi Ikarashi, Masaki Shimono, Han-Sung Jung, Takashi Muramatsu   +5 more
doaj   +1 more source

In vivo fate of bone marrow mesenchymal stem cells implanted into rat pulpotomized molars

Stem Cell Research, 2019
In our previous work, we established an in vivo coronal pulp regeneration model in which biodegradable hydrogel-made scaffolds carrying rat bone marrow mesenchymal stem cells (BM-MSCs) were implanted in the coronal pulp chamber of pulpotomized rat ...
Tomoatsu Kaneko, Phyo Pyai Sone, Su Yee Myo Zaw, Yukikio Sueyama, Zar Chi Thein Zaw, Yamato Okada, Hiroki Murano, Bin Gu, Takashi Okiji   +8 more
doaj   +1 more source

Involvement of M1/M2 Macrophage Polarization in Reparative Dentin Formation

Life, 2022
In cases in which dental pulp tissue is accidentally exposed, direct pulp capping is often performed to induce reparative dentin formation. Although macrophages are essential for the inflammatory response and tissue repair, the emergence pattern and the ...
Masataka Kadowaki, Shinichiro Yoshida, Tomohiro Itoyama, Atsushi Tomokiyo, Sayuri Hamano, Daigaku Hasegawa, Hideki Sugii, Hiroshi Kaneko, Risa Sugiura, Hidefumi Maeda   +9 more
doaj   +1 more source

Bioactive molecules for regenerative pulp capping [PDF]

European Cells & Materials, 2021
Since the discovery of bioactive molecules sequestered in dentine, researchers have been exploring ways to harness their activities for dental regeneration. One specific area, discussed in this review, is that of dental-pulp capping. Dental-pulp caps are
LLE Whitehouse, NH Thomson, T Do, GA Feichtinger   +3 more
doaj   +1 more source

Analysis of Torque and Force Induced by Rotary Nickel-Titanium Instruments during Root Canal Preparation: A Systematic Review

Applied Sciences, 2021
The aim of this review was to provide a detailed literature analysis of torque and force generation during nickel-titanium rotary root canal instrumentation.
Myint Thu, Arata Ebihara, Sherif Adel, Takashi Okiji   +3 more
doaj   +1 more source

Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro

Journal of Dental Sciences, 2023
Background/purpose: The mineralized tissue-inductive ability and anti-inflammatory properties of hydraulic calcium silicate-based (HCSB) sealers have not been fully elucidated.
Aseel Alchawoosh, Kentaro Hashimoto, Nobuyuki Kawashima, Sonoko Noda, Kosuke Nozaki, Takashi Okiji   +5 more
doaj   +1 more source

Current and future options for dental pulp therapy

Japanese Dental Science Review, 2019
Summary: Dental pulp is a connective tissue and has functions that include initiative, formative, protective, nutritive, and reparative activities. However, it has relatively low compliance, because it is enclosed in hard tissue.
Takahiko Morotomi, Ayako Washio, Chiaki Kitamura   +2 more
doaj   +1 more source

Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules

Indonesian Biomedical Journal, 2023
BACKGROUND: Pulp damage can lead to dentinogenesis impairment, irreversible pulpitis, or pulp necrosis. Despite being the most used endodontic procedure to treat damaged pulp, root canal therapy only results in nonvital teeth which are prone to fractures
Ferry Sandra, Andri Sutanto, Widya Wulandari, Reynaldo Lambertus, Maria Celinna, Nurrani Mustika Dewi, Solachuddin Jauhari Arief Ichwan   +6 more
doaj   +1 more source