Creating a Microenvironment to Give Wings to Dental Pulp Regeneration—Bioactive Scaffolds [PDF]
Pharmaceutics, 2023 Dental pulp and periapical diseases make patients suffer from acute pain and economic loss. Although root canal therapies, as demonstrated through evidence-based medicine, can relieve symptoms and are commonly employed by dentists, it is still difficult ...
Nan Hu +4 more
doaj +5 more sources
Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which ...
Jiahui Fu +8 more
doaj +5 more sources
Microenvironment Influences Odontogenic Mesenchymal Stem Cells Mediated Dental Pulp Regeneration [PDF]
Frontiers in Physiology, 2021 Dental pulp as a source of nutrition for the whole tooth is vulnerable to trauma and bacterial invasion, which causes irreversible pulpitis and pulp necrosis. Dental pulp regeneration is a valuable method of restoring the viability of the dental pulp and
Xiaoyao Huang +26 more
doaj +4 more sources
In vitro, ex vivo, and in vivo models for dental pulp regeneration [PDF]
Journal of Materials Science: Materials in Medicine, 2023 Based on the concept of tissue engineering (Cells—Scaffold—Bioactive molecules), regenerative endodontics appeared as a new notion for dental endodontic treatment.
Sofia Silvia Piglionico +5 more
doaj +3 more sources
Dental Pulp Stem Cell–Derived Multicellular Microtissue Spheres: A Synergistic Strategy for Dental Pulp Regeneration [PDF]
International Dental JournalObjective: Restoring pulp tissue to its natural state is the ultimate goal of pulp regeneration, during which vascularization and neuralization of regenerated pulp are key factors.
Wei Jian +8 more
doaj +3 more sources
Mapping global research in dental pulp regeneration: A 10-year bibliometric analysis [PDF]
Dental Research JournalBackground: Dental pulp regeneration aims to restore the function and vitality of the dental pulp, which is the soft tissue inside the tooth. Research in this field is effective in trying to improve clinical practices and procedures.
Yeganeh-Sadat Mostafavi +5 more
doaj +3 more sources
Chemically modified microRNA delivery via DNA tetrahedral frameworks for dental pulp regeneration [PDF]
Journal of NanobiotechnologyDental pulp regeneration is a promising strategy for addressing tooth disorders. Incorporating this strategy involves the fundamental challenge of establishing functional vascular networks using dental pulp stem cells (DPSCs) to support tissue ...
Xiaoling Wei +5 more
doaj +2 more sources
Decellularized rat submandibular gland as an alternative scaffold for dental pulp regeneration [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Decellularized extracellular matrix has been recognized as an optimal scaffold for dental pulp regeneration. However, the limited amount of native dental pulp tissue restricts its clinical applications.
Yuanyuan Shi +3 more
doaj +2 more sources
Biomaterials and Biosystems, 2023 Mesenchymal stromal/stem cell (MSC) therapies are currently being explored for dental pulp regeneration. As the therapeutic effects of MSCs in tissue repair are mediated mainly through the release of extracellular vesicles (EVs) including exosomes, we ...
Jiajun Shi +8 more
doaj +3 more sources
An Electrospun Heparin Modified Nanofiber Membrane Carrying Multiple Growth Factors for Dental Pulp Regeneration [PDF]
International Dental JournalIntroduction and aims: To develop a multifunctional nanofiber membrane carrying angiogenic, dentinogenic, and neurogenic growth factors for dental pulp regeneration.
Xin-Lu Li, Hui Liu, Wei Fan, Bing Fan
doaj +2 more sources