Pulp regeneration: Current approaches and future challenges [PDF]
Frontiers in Physiology, 2016 Regenerative endodontics aims to replace inflamed/necrotic pulp tissues with regenerated pulp-like tissues to revitalize teeth and improve life quality.
Jingwen eYANG +4 more
doaj +4 more sources
Scaffolds for Dentin–Pulp Complex Regeneration
Medicina, 2023 Background and Objectives: Regenerative dentistry aims to regenerate the pulp–dentin complex and restore those of its functions that have become compromised by pulp injury and/or inflammation.
Diana B. Sequeira +4 more
doaj +4 more sources
Infection and Pulp Regeneration [PDF]
Dentistry Journal, 2016 The regeneration of the pulp-dentin complex has been a great challenge to both scientists and clinicians. Previous work has shown that the presence of prior infection may influence the characteristics of tissues formed in the root canal space after regenerative endodontic treatment.
Sahng G Kim
exaly +7 more sources
Dental pulp regeneration strategies: A review of status quo and recent advances [PDF]
Bioactive MaterialsMicroorganisms, physical factors such as temperature or mechanical injury, and chemical factors such as free monomers from composite resin are the main causes of dental pulp diseases.
Bing Fan, Wei Fan
exaly +4 more sources
Dental Pulp Stem Cell–Derived Multicellular Microtissue Spheres: A Synergistic Strategy for Dental Pulp Regeneration [PDF]
International Dental JournalObjective: Restoring pulp tissue to its natural state is the ultimate goal of pulp regeneration, during which vascularization and neuralization of regenerated pulp are key factors.
Wei Jian +8 more
doaj +3 more sources
Extracellular Vesicles for Dental Pulp and Periodontal Regeneration
Pharmaceutics, 2023 Extracellular vesicles (EVs) are lipid bound particles derived from their original cells, which play critical roles in intercellular communication through their cargoes, including protein, lipids, and nucleic acids.
Xiaoxing Kou, Xueli Mao, Lai Hongbin
exaly +4 more sources
Application of neurotransmitters and dental stem cells for pulp regeneration: A review [PDF]
Saudi Dental Journal, 2023 Introduction: Although there have been many studies on stem cells, few have investigated how neurotransmitters and stem cell proliferation interact to regenerate dental pulp.
Hidayah Ramli +5 more
doaj +2 more sources
Conditioned medium from the inflammatory microenvironment of human dental pulp stem cells regulated functional pulp regeneration [PDF]
BMC Oral HealthObjective This study explored the effects of inflammatory microenvironment on stem cells from the apical papilla (SCAP) for cell homing strategy-based pulp regeneration.
Qian Zhang +6 more
doaj +2 more sources
Extracellular Vesicles Derived from Human CD24+ Dental Papilla Stem Cells Promote Vascularized Dental Pulp Regeneration [PDF]
BiomoleculesPulp necrosis remains a significant clinical challenge in dentistry, as current therapeutic approaches fail to achieve functional pulp regeneration.
Jie Li +6 more
doaj +2 more sources
A carbon dot nanozyme hydrogel enhances pulp regeneration activity by regulating oxidative stress in dental pulpitis [PDF]
Journal of NanobiotechnologyPreserving pulp viability and promoting pulp regeneration in pulpitis have attracted widespread attention. Restricted by the oxidative stress microenvironment of dental pulpitis, excessive reactive oxygen and nitrogen species (RONS) trigger uncontrolled ...
Yingjuan Zhang +9 more
doaj +2 more sources