Results 31 to 40 of about 561,418 (271)

Atlas of human dental pulp cells at multiple spatial and temporal levels based on single-cell sequencing analysis

open access: yesFrontiers in Physiology, 2022
The dental pulp plays a crucial role in the long-term maintenance of tooth function. The progress of endodontic treatment and pulp tissue regeneration engineering has made pulp-regeneration therapy promising in clinical practice.
Huihui Ren   +4 more
doaj   +1 more source

Pulp Stem Cell–Mediated Functional Pulp Regeneration [PDF]

open access: yesJournal of Dental Research, 2018
The preservation of vital dental pulp with vasculature and nerve components remains one of the most significant challenges in modern dentistry. Due to the immense potential for neurovascularization, mesenchymal stem cell (MSC) transplantation has shown emerging promise in regenerative medicine and dental translational practice.
B, Sui   +6 more
openaire   +2 more sources

In Vivo Evaluation of Decellularized Human Tooth Scaffold for Dental Tissue Regeneration

open access: yesApplied Sciences, 2021
Conventional root canal treatment may result in loss of tooth vitality, which can lead to unfavorable treatment outcomes. Notably, a ceased tooth development of immature permanent teeth with open apices, regeneration of periodontal ligaments (PDL), and ...
Ik-Hwan Kim   +11 more
doaj   +1 more source

Prevascularization techniques for dental pulp regeneration: potential cell sources, intercellular communication and construction strategies

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
One of the difficulties of pulp regeneration is the rapid vascularization of transplanted engineered tissue, which is crucial for the initial survival of the graft and subsequent pulp regeneration.
Qiao Ruan   +4 more
doaj   +1 more source

Research progress of pulpotomy and crown pulp regeneration

open access: yes口腔疾病防治, 2019
Crown pulp regeneration is a method to replace the pulp-capping agent with stem cells and scaffold structures, which are placed on the section of healthy root pulp tissue after pulpotomy to regenerate the pulp-dentin complex in the crown.
QIU Ying, LI Xiangwei
doaj   +1 more source

Research progress of scaffolds for promoting the vascularization of regenerated dental pulp

open access: yes口腔疾病防治, 2020
Endothelial regeneration is a research hotspot in the field of dental pulp. The regeneration of endodontic blood flow is the bottleneck of dental pulp regeneration, and the applied scaffold material is the key to revascularization.
LIU Huimin, LI Xiangwei
doaj   +1 more source

Is Pulp Inflammation a Prerequisite for Pulp Healing and Regeneration?

open access: yesMediators of Inflammation, 2015
The importance of inflammation has been underestimated in pulpal healing, and in the past, it has been considered only as an undesirable effect. Associated with moderate inflammation, necrosis includes pyroptosis, apoptosis, and nemosis. There are now evidences that inflammation is a prerequisite for pulp healing, with series of events ahead of ...
Uzunoglu, EMEL   +2 more
openaire   +5 more sources

Research progress and challenges of pulp regeneration in mature permanent teeth [PDF]

open access: yesKouqiang yixue
This paper focuses on the transformation of pulp regeneration technology from being limited to young permanent teeth to being extended to mature permanent teeth, and elaborates on the research progress and challenges of pulp regeneration in mature ...
HU Longxin, MU Haili, ZHANG Jihao, SHI Xiaorui
doaj   +1 more source

Pulp/Dentin Regeneration: It Should Be Complicated

open access: yesJournal of Endodontics, 2020
Stem cell-mediated regenerative endodontics has reached the human clinical trial phase; however, many issues still exist that prevent such technology to be a widely used clinical practice. These issues are not straightforward and are complicated. They should be because pulp regeneration is dealing with a small dead-end space.
George T-J, Huang   +6 more
openaire   +3 more sources

Local Regeneration of Dentin-Pulp Complex Using Controlled Release of FGF-2 and Naturally Derived Sponge-Like Scaffolds

open access: yesInternational Journal of Dentistry, 2012
Restorative and endodontic procedures have been recently developed in an attempt to preserve the vitality of dental pulp after exposure to external stimuli, such as caries infection or traumatic injury.
Chiaki Kitamura   +4 more
doaj   +1 more source

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