Clinical Perspectives of Pulp Regeneration [PDF]
A sound and vital pulp is an essential prerequisite for long-term tooth survival and preservation. However, current endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by a synthetic biomaterial. Recently, total or partial pulp regeneration has been proposed as an alternative treatment concept.
Schmalz G, Widbiller M, Galler KM
openaire +5 more sources
Decellularized Swine Dental Pulp as a Bioscaffold for Pulp Regeneration [PDF]
Endodontic regeneration shows promise in treating dental pulp diseases; however, no suitable scaffolds exist for pulp regeneration. Acellular natural extracellular matrix (ECM) is a favorable scaffold for tissue regeneration since the anatomical structure and ECM of the natural tissues or organs are well-preserved.
Lei Hu +7 more
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Research progress of scaffold materials for dental pulp regeneration [PDF]
Pulp regeneration is currently a hot topic in pulp disease research. With the development of regenerative medicine, pulp regeneration is transitioning from basic research to clinical applications, and stable results have been observed in some cases ...
LIU Yuan, YAN Yanhong, JIANG Beizhan
doaj +2 more sources
The Microbial Challenge to Pulp Regeneration [PDF]
Pulp regeneration is considered in cases where the dental pulp has been destroyed because of microbial irritation. Diverse oral and food-borne micro-organisms are able to invade the pulp space, form biofilm on canal walls, and infiltrate dentinal tubules.
A.F. Fouad
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Potential Therapeutic Strategy of Targeting Pulp Fibroblasts in Dentin-Pulp Regeneration [PDF]
Fibroblasts represent the most abundant population within the dental pulp. Although other cell types such as odontoblasts and stem cells have been extensively investigated, very little attention was given to the fibroblasts, which have major roles in regulating the pulp biology and function under normal and pathologic conditions.
Jeanneau, Charlotte +3 more
openaire +7 more sources
Human CD24+ dental papilla cells are competent seed cells for dentin-pulp regeneration via BMP2/SIRT1 axis [PDF]
Regeneration of the dentin-pulp complex is essential for tooth integrity and function. However, the inherent cell heterogeneity limits our understanding of lineage-specific subsets critical for efficient odontogenesis and regenerative outcomes.
Cheng Liang +16 more
doaj +2 more sources
Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration [PDF]
Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which ...
Jiahui Fu +8 more
doaj +3 more sources
A Compilation of Study Models for Dental Pulp Regeneration. [PDF]
Efforts to heal damaged pulp tissue through tissue engineering have produced positive results in pilot trials. However, the differentiation between real regeneration and mere repair is not possible through clinical measures. Therefore, preclinical study models are still of great importance, both to gain insights into treatment outcomes on tissue and ...
Ohlsson E, Galler KM, Widbiller M.
europepmc +4 more sources
Mapping global research in dental pulp regeneration: A 10-year bibliometric analysis [PDF]
Background: Dental pulp regeneration aims to restore the function and vitality of the dental pulp, which is the soft tissue inside the tooth. Research in this field is effective in trying to improve clinical practices and procedures.
Yeganeh-Sadat Mostafavi +5 more
doaj +2 more sources
Chemically modified microRNA delivery via DNA tetrahedral frameworks for dental pulp regeneration [PDF]
Dental pulp regeneration is a promising strategy for addressing tooth disorders. Incorporating this strategy involves the fundamental challenge of establishing functional vascular networks using dental pulp stem cells (DPSCs) to support tissue ...
Xiaoling Wei +5 more
doaj +2 more sources

