Results 41 to 50 of about 561,418 (271)
Biomaterials and Biosystems, 2023 Mesenchymal stromal/stem cell (MSC) therapies are currently being explored for dental pulp regeneration. As the therapeutic effects of MSCs in tissue repair are mediated mainly through the release of extracellular vesicles (EVs) including exosomes, we ...
Jiajun Shi +8 more
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Hydrogel Scaffold in Pulp Dentin Complex Regeneration [PDF]
, 2022 Pulp dentin complex regeneration can be initiated by hydrogel scaffold application in the pulp using tissue engineering concept and it gives many advantages.
Elline, - +2 more
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Trigeminal Sensory Neurons and Pulp Regeneration [PDF]
Journal of Endodontics, 2020 The pulp-dentin complex is innervated by a high density of trigeminal neurons free nerve endings. These neuronal fibers are highly specialized to sense noxious stimuli such as thermal, mechanical, chemical, and biological cues. This robust alert system provides immediate feedback of potential or actual injury triggering reflex responses that protect ...
openaire +2 more sources
Advances in signal pathways related to pulp regeneration mediated by exosomes [PDF]
Kouqiang yixueExosomes are a kind of extracellular vesicles, which directly stimulate target cells through receptor-mediated interaction, or exert their biological functions by transferring various bioactive molecules to target cells, playing a key role in ...
CHEN Zirong, TU Hua, CHEN Leyi, XU Wen’an
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Materials Today Bio, 2022 Dental pulp necrosis are serious pathologic entities that causes tooth nutrition deficiency and abnormal root development, while regeneration of functional pulp tissue is of paramount importance to regain tooth vitality.
Xiaojing Yuan +11 more
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The research progress of regenerative endodontic treatment for immature permanent teeth
口腔疾病防治, 2016 The pulpal or periapical diseases of immature permanent teeth often lead to incomplete root development. It is a challenge for us to figure out how to ensure the continuous growth of the teeth and the formation of roots.
SONG Guang-tai, JIN Qiu-chen
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Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules [PDF]
, 2023 BACKGROUND: Pulp damage can lead to dentinogenesis impairment, irreversible pulpitis, or pulp necrosis. Despite being the most used endodontic procedure to treat damaged pulp, root canal therapy only results in nonvital teeth which are prone to fractures
Sandra, Ferry +13 more
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The research progress of dental pulp regeneration
口腔疾病防治, 2016 Living pulp is crucial for the maintenance of tooth homeostasis. An ideal form should consist of regenerative approaches, which necrotic pulp or diseased tissues are replaced with regenerated pulp tissues, and the tooth converts into vital in the end ...
TAN Zhong-juan +2 more
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Endogenous Trigeminal Neurons Induce Schwann Differentiation of Donor Stem Cells in Dental Pulp Regeneration via Reciprocal Extracellular Vesicles Interplay [PDF]
Exploration (Beijing)Our study demonstrates that the host TG coordinates with heterologously implanted SHED to regenerate functional dental pulp through reciprocal EVs’ interplay. EVs derived from implanted stem cells migrate to the host TG to activate axonal regeneration.
Zhao W +12 more
europepmc +2 more sources
New treatment modality for pulpititis and apical periodontitis: pathway of regenerative endodontics
口腔疾病防治, 2017 Tissue engineering has been applied to induce pulp⁃dentin complex regeneration, and proposed the con⁃ cept of regenerative endodontics. As a new subject in stomatology, regenerative endodontics promotes root development and pulp regeneration with the ...
YANG Mao⁃ bin, ZENG Qian
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