Results 11 to 20 of about 58,603 (315)

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Karol Ramírez, Dima A. Sabbah, Camille Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
openalex   +2 more sources

Mechanobiology of Dental Pulp Cells

Cells
The dental pulp is the inner part of the tooth responsible for properly functioning during its lifespan. Apart from the very big biological heterogeneity of dental cells, tooth microenvironments differ a lot in the context of mechanical properties ...
Natalia Bryniarska-Kubiak, Agnieszka Basta-Kaim, Andrzej Kubiak   +2 more
doaj   +3 more sources

Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which were essential for odontoblast differentiation.
Jiahui Fu, Jianfeng Chen, Wenjun Li, Xiaomin Yang, Jingyan Yang, Huixin Quan, Haitao Huang, Gang Chen, Gang Chen   +8 more
openaire   +3 more sources

Effect of different axial speed patterns on cyclic fatigue resistance of rotary nickel-titanium instruments

BMC Oral Health, 2022
Background To evaluate the effect of pecking motions with faster upward speed on the dynamic cyclic fatigue resistance of nickel-titanium rotary instruments with different metallurgy. Methods Forty each of ProTaper Universal F3 (PTU) and ProTaper Gold F3
Myint Thu, Arata Ebihara, Keiichiro Maki, Miki Nishijo, Shunsuke Kimura, Taro Nakatsukasa, Moe Sandar Kyaw, Takashi Okiji   +7 more
doaj   +1 more source

Microenvironment Influences Odontogenic Mesenchymal Stem Cells Mediated Dental Pulp Regeneration

Frontiers in Physiology, 2021
Dental pulp as a source of nutrition for the whole tooth is vulnerable to trauma and bacterial invasion, which causes irreversible pulpitis and pulp necrosis. Dental pulp regeneration is a valuable method of restoring the viability of the dental pulp and
Xiaoyao Huang, Xiaoyao Huang, Xiaoyao Huang, Zihan Li, Zihan Li, Zihan Li, Anqi Liu, Anqi Liu, Anqi Liu, Xuemei Liu, Xuemei Liu, Xuemei Liu, Hao Guo, Hao Guo, Hao Guo, Meiling Wu, Meiling Wu, Meiling Wu, Xiaoxue Yang, Xiaoxue Yang, Xiaoxue Yang, Bing Han, Bing Han, Bing Han, Kun Xuan, Kun Xuan, Kun Xuan   +26 more
doaj   +1 more source

Phase transformation and mechanical properties of heat-treated nickel-titanium rotary endodontic instruments at room and body temperatures

BMC Oral Health, 2023
Background The aim of this study was to evaluate the phase composition, phase transformation temperatures, bending property, and cyclic fatigue resistance of different heat-treated nickel-titanium (NiTi) rotary instruments with the same tip diameter and ...
Yuka Kasuga, Shunsuke Kimura, Keiichiro Maki, Hayate Unno, Satoshi Omori, Keiko Hirano, Arata Ebihara, Takashi Okiji   +7 more
doaj   +1 more source

Dynamic torque and screw-in force of four different glide path instruments assessed in simulated single- and double-curved canals: An in vitro study

Journal of Dental Sciences, 2023
Background/purpose: The glide path instruments are the introductory instruments into the canals; thus, they should be durable enough to withstand torsional stress/screw-in force.
Myint Thu, Arata Ebihara, Keiichiro Maki, Shunsuke Kimura, Moe-Sandar Kyaw, Yuka Kasuga, Miki Nishijo, Takashi Okiji   +7 more
doaj   +1 more source

Influence of different kinematics on stationary and dynamic torsional behavior of JIZAI nickel-titanium rotary instruments: An in vitro study

Journal of Dental Sciences, 2023
Background/purpose: Using conventional approach to examine stationary torque of nickel-titanium rotary instruments contradicts the clinical condition, and its validity for motions involving clockwise and counterclockwise rotations is questionable.
Myint Thu, Arata Ebihara, Moe Sandar Kyaw, Satoshi Omori, Keiichiro Maki, Shunsuke Kimura, Hayate Unno, Takashi Okiji   +7 more
doaj   +1 more source

Comparison of vapor bubble kinetics and cleaning efficacy of different root canal irrigation techniques in the apical area beyond the fractured instrument

Journal of Dental Sciences, 2023
Background/purpose: Intracanal fractured instruments hamper adequate root canal disinfection. The aim of this study was to evaluate vapor bubble kinetics and cleaning efficacy of different irrigation techniques in the apical area beyond the fractured ...
Jiayi Liu, Satoshi Watanabe, Sota Mochizuki, Akira Kouno, Takashi Okiji   +4 more
doaj   +1 more source

Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9

Scientific Reports, 2022
Accelerated dental pulp mineralization is a common complication in avulsed/luxated teeth, although the mechanisms underlying this remain unclear. We hypothesized that hypoxia due to vascular severance may induce osteo/odontoblast differentiation of ...
Shion Orikasa, Nobuyuki Kawashima, Kento Tazawa, Kentaro Hashimoto, Keisuke Sunada-Nara, Sonoko Noda, Mayuko Fujii, Tetsu Akiyama, Takashi Okiji   +8 more
doaj   +1 more source