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Mechanobiology of Dental Pulp Cells
CellsThe dental pulp is the inner part of the tooth responsible for properly functioning during its lifespan. Apart from the very big biological heterogeneity of dental cells, tooth microenvironments differ a lot in the context of mechanical properties ...
Natalia Bryniarska-Kubiak +2 more
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Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which were essential for odontoblast differentiation.
Jiahui Fu +8 more
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Inflammation of the Dental Pulp [PDF]
Mediators of Inflammation, 2015 The dental pulp is sensitive to external factors such as microbial infection from dental caries and/or mechanical/chemical irritations during dental procedures. Dental tissue behaves differently to the other connective tissues. It is unique in a way that its soft tissues (pulp and pulp-dentin complex) are enclosed within mineralized hard tissues ...
Park, Sang Hyuk +4 more
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Journal of Dental Sciences, 2021 Background/purpose: Laser-activated root canal irrigation (LAI) with an Er:YAG laser is considered more effective than other irrigation methods, whereas the effectiveness of LAI in cleaning lateral canals far from the laser tip remains unclear.
Yasuhiro Hoshihara +4 more
doaj +1 more source
Frontiers in Dental Medicine, 2022 Regenerative endodontic cell-homing procedures are frequently performed on injured immature teeth diagnosed with pulp necrosis and/or apical periodontitis. The representative histological finding after those procedures is cementum-like tissues filling in
Tomoaki Komada +5 more
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Bioactive molecules for regenerative pulp capping [PDF]
European Cells & Materials, 2021 Since the discovery of bioactive molecules sequestered in dentine, researchers have been exploring ways to harness their activities for dental regeneration. One specific area, discussed in this review, is that of dental-pulp capping. Dental-pulp caps are
LLE Whitehouse +3 more
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In vivo fate of bone marrow mesenchymal stem cells implanted into rat pulpotomized molars
Stem Cell Research, 2019 In our previous work, we established an in vivo coronal pulp regeneration model in which biodegradable hydrogel-made scaffolds carrying rat bone marrow mesenchymal stem cells (BM-MSCs) were implanted in the coronal pulp chamber of pulpotomized rat ...
Tomoatsu Kaneko +8 more
doaj +1 more source
Nanomagnetic-Mediated Drug Delivery for The Treatment of Dental Disease [PDF]
, 2018 Maintaining the vitality of the dental pulp, the highly innervated and highly vascular, innermost layer of the tooth, is a critical goal of any dental procedure. Upon injury, targeting the pulp with specific therapies is challenging because it is encased
Choi, Seung K. +12 more
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Dental pulp tissue engineering [PDF]
Brazilian Dental Journal, 2011 Dental pulp is a highly specialized mesenchymal tissue that has a limited regeneration capacity due to anatomical arrangement and post-mitotic nature of odontoblastic cells. Entire pulp amputation followed by pulp space disinfection and filling with an artificial material cause loss of a significant amount of dentin leaving as life-lasting sequelae a ...
Demarco, Flávio Fernando +5 more
openaire +6 more sources
Involvement of M1/M2 Macrophage Polarization in Reparative Dentin Formation
Life, 2022 In cases in which dental pulp tissue is accidentally exposed, direct pulp capping is often performed to induce reparative dentin formation. Although macrophages are essential for the inflammatory response and tissue repair, the emergence pattern and the ...
Masataka Kadowaki +9 more
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