Dental pulp stem cells as a promising model to study imprinting diseases [PDF]
Parental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are characterized by growth and metabolic issues starting from birth to adulthood. They are mainly due
Eloïse Giabicani+9 more
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Dental pulp stem cells for treating neurodegenerative diseases
The hippocampal formation, important for spatial learning and memory function, exhibits high level of plasticity in response to behavioral changes as well as injury. Dysfunction of the hippocampus is one of the hallmark features of neurodegenerative diseases like temporal lobe epilepsy (TLE) and Alzheimer's disease (AD) (Dhanushkodi and Shetty 2008 ...
Christopher Shamir+2 more
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Alzheimer’s disease: Pathophysiology and dental pulp stem cells therapeutic prospects [PDF]
Alzheimer’s disease (AD) is a destructive neurodegenerative disease with the progressive dysfunction, structural disorders and decreased numbers of neurons in the brain, which leads to long-term memory impairment and cognitive decline. There is a growing consensus that the development of AD has several molecular mechanisms similar to those of other ...
Wei Xiong+5 more
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Therapeutic potential of dental pulp stem cell transplantation in a rat model of Alzheimer’s disease
Dental pulp stem cells are dental pulp-derived mesenchymal stem cells that originate from the neural crest. They exhibit greater potential for the treatment of nervous system diseases than other types of stem cells because of their neurogenic ...
Xue-Mei Zhang+14 more
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Characteristics and Therapeutic Potential of Dental Pulp Stem Cells on Neurodegenerative Diseases [PDF]
To evaluate the therapeutic potential of stem cells for neurodegenerative diseases, emphasis should be placed on clarifying the characteristics of the various types of stem cells. Among stem cells, dental pulp stem cells (DPSCs) are a cell population that is rich in cell proliferation and multipotency. It has been reported that transplantation of DPSCs
Tomoyuki Ueda+4 more
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The Histlogical Comparison of Pulp Disease between Dental Trauma and Pulp Exposure
The aim of this study was to investigate the histological changes of dental pulp following luxation of tooth, and compared with that of pulp exposure mechanically. Upper left first molar of twenty male, 5 weeks age, Wister rats were used for this study; ten were used for trauma group by luxation and ten for mechanically expose group.
Yoshishige Yamada, Koukichi Matsumoto
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Background/purpose: The penetration rate of National Health Insurance (NHI) of Taiwan is as high as 99.9%. This study investigated the profile of dental use for diseases of pulp and periapical tissues under the NHI system of Taiwan in 2020. Materials and
Feng-Chou Cheng, Chun-Pin Chiang
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Human dental pulp stem cells derived from different cryopreservation methods of human dental pulp tissues of diseased teeth [PDF]
Successful isolation of human dental pulp stem cells (hDPSCs) has been documented at least 120h after tooth extraction. Viable hDPSCs have been isolated chiefly from cryopreserved healthy molar teeth and their undigested dental pulp tissue. Isolation of hDPSCs from diseased but vital teeth after cryopreservation has not been reported.
Yuk-Kwan Chen+4 more
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Therapeutic potential of curcumin in regenerative dentistry [PDF]
IntroductionNatural compounds have emerged as promising candidates in drug development due to their potent immunomodulatory anti-inflammatory, antibacterial, analgesic, and healing properties. They have shown significant therapeutic potential in clinical
Anahid A. Birjandi, Paul Sharpe
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Dental pulp stones and their correlation with metabolic diseases
Abstract Background: Dental pulp calcifications or pulp stones are calcified structures found in dental pulp, mostly around or enclosing a blood vessel. The formation of these calcifications begins with concentric layers of calcified tissue within which remnants of necrotic and calcified cells may be present.
Mohammad Imran Khan+5 more
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