Results 41 to 50 of about 22,501 (299)

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

open access: yesAdvanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim   +2 more
wiley   +1 more source

Dental Tissue-Derived Human Mesenchymal Stem Cells and Their Potential in Therapeutic Application

open access: yesStem Cells International, 2020
Human mesenchymal stem cells (hMSCs) are multipotent cells, which exhibit plastic adherence, express specific cell surface marker spectrum, and have multi-lineage differentiation potential. These cells can be obtained from multiple tissues. Dental tissue-
Lu Gan   +5 more
doaj   +1 more source

Isolamento e caracterização de células-tronco humanas do saco pericoronário de dentes permanentes subjacentes aos decíduos esfoliados - SUED [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em OdontologiaA descoberta da presença de células-tronco em tecidos odontológicos abre uma nova frente de trabalho e de estudo aos ...
Leão, Moira Pedroso
core  

Macrophage Phenotype Detection Methodology on Textured Surfaces via Nuclear Morphology Using Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi   +5 more
wiley   +1 more source

Pulp and periapical diseases in permanent dental structures of patients aged six to fourteen years

open access: yesRevista Cubana de Estomatología, 2017
Introduction: when permanent dental structures have young, immature pulps, they are bigger and their root canal walls are very thin. If they are affected by some pulp or periapical disease, damage is caused to pulp integrity and consequently to root ...
Celia Elena Mendiburu Zavala   +3 more
doaj  

Cell therapy comparison of dental pulp stem cells, hepatocytes, and their exosomes for liver fibrosis treatment in rats

open access: yesAnimal Models and Experimental Medicine, EarlyView.
DPSCs, hepatocytes, and exosomes were tested for liver fibrosis therapy. Exosome‐based treatment exhibited superior antioxidative and regenerative effects. Liver enzymes, oxidative stress, and profibrotic markers were significantly reduced. α‐SMA, desmin, and related gene expression were downregulated.
Sahar Rahimi   +3 more
wiley   +1 more source

IL-1β induced IL-8 and uPA expression/production of dental pulp cells: Role of TAK1 and MEK/ERK signaling

open access: yesJournal of the Formosan Medical Association, 2018
Background/purpose: Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine involved in the inflammatory processes of dental pulp. IL-8 and urokinase plasminogen activator (uPA) are two inflammatory mediators.
Szu-I Lin   +8 more
doaj   +1 more source

Células-tronco: importância e perpectivas na Odontologia [PDF]

open access: yes, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Não há dúvida acerca do extenso conhecimento da Odontologia no que se refere à patologia dentária e àsua reabilitação, utilizando materiais restauradores ...
Gobbi, Thais Rockenbach
core  

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li   +11 more
wiley   +1 more source

Dental pulp stem cells: Potential significance in regenerative medicine

open access: yes, 2008
To date, three types of dental stem cells have been isolated: Dental Pulp Stem Cells (DPSC), Stem Cells From Human Exfoliated Deciduous Teeth (SHED) and Immature Dental Pulp Stem Cells (IDPC).
Petakov Marijana   +9 more
core   +1 more source

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