Dental pulp stem cells as a promising model to study imprinting diseases
International Journal of Oral Science, 2022 Parental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting diseases are characterized by growth and metabolic issues starting from birth to adulthood. They are mainly due
Eloïse Giabicani +9 more
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Creating a Microenvironment to Give Wings to Dental Pulp Regeneration—Bioactive Scaffolds
Pharmaceutics, 2023 Dental pulp and periapical diseases make patients suffer from acute pain and economic loss. Although root canal therapies, as demonstrated through evidence-based medicine, can relieve symptoms and are commonly employed by dentists, it is still difficult ...
Nan Hu +4 more
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Immunomodulatory Mechanism and Potential Application of Dental Pulp-Derived Stem Cells in Immune-Mediated Diseases [PDF]
International Journal of Molecular Sciences, 2023 Dental pulp stem cells (DPSCs) are mesenchymal stem cells (MSCs) derived from dental pulp tissue, which have high self-renewal ability and multi-lineage differentiation potential.
Min Qi +5 more
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Regenerative medicine using dental pulp stem cells for liver diseases
World Journal of Gastrointestinal Pharmacology and Therapeutics, 2017 Acute liver failure is a refractory disease and its prognosis, if not treated using liver transplantation, is extremely poor. It is a good candidate for regenerative medicine, where stem cell-based therapies play a central role. Mesenchymal stem cells (MSCs) are known to differentiate into multiple cell lineages including hepatocytes.
Ohkoshi, Shogo +4 more
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Dental pulp stones and their correlation with metabolic diseases
Journal of Oral and Maxillofacial PathologyAbstract Background: Dental pulp calcifications or pulp stones are calcified structures found in dental pulp, mostly around or enclosing a blood vessel. The formation of these calcifications begins with concentric layers of calcified tissue within which remnants of necrotic and calcified cells may be present.
Khan, Mohammad Imran +5 more
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International Journal of Clinical Pediatric Dentistry, 2023 Background Dental pain due to pulpal involvement is difficult to diagnose due to the apparent inaccessibility of pulp to the clinical tests, indistinct symptoms, and referred toothache originating from the periodontal tissues.
Kanika Singh Dhull +5 more
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Characteristics and Therapeutic Potential of Dental Pulp Stem Cells on Neurodegenerative Diseases [PDF]
Frontiers in Neuroscience, 2020 To evaluate the therapeutic potential of stem cells for neurodegenerative diseases, emphasis should be placed on clarifying the characteristics of the various types of stem cells.
Tomoyuki Ueda +4 more
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Clinical Potential and Current Progress of Dental Pulp Stem Cells for Various Systemic Diseases in Regenerative Medicine: A Concise Review [PDF]
International Journal of Molecular Sciences, 2019 Dental pulp stem cells (DPSCs) are mesenchymal stem cells (MSCs) that have multipotent differentiation and a self-renewal ability. They have been useful not only for dental diseases, but also for systemic diseases.
Yoichi Yamada +3 more
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Human dental pulp stem cells mitigate the neuropathology and cognitive decline via AKT-GSK3β-Nrf2 pathways in Alzheimer’s disease [PDF]
International Journal of Oral ScienceOxidative stress is increasingly recognized as a major contributor to the pathophysiology of Alzheimer’s disease (AD), particularly in the early stages of the disease.
Wei Xiong +8 more
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The Therapeutic Potential of Secreted Factors from Dental Pulp Stem Cells for Various Diseases
Biomedicines, 2022 An alternative source of mesenchymal stem cells has recently been discovered: dental pulp stem cells (DPSCs), including deciduous teeth, which can thus comprise potential tools for regenerative medicine.
Kenichi Ogata +5 more
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