Results 61 to 70 of about 60,050 (369)

Dental Tissue-Derived Human Mesenchymal Stem Cells and Their Potential in Therapeutic Application

Stem Cells International, 2020
Human mesenchymal stem cells (hMSCs) are multipotent cells, which exhibit plastic adherence, express specific cell surface marker spectrum, and have multi-lineage differentiation potential. These cells can be obtained from multiple tissues. Dental tissue-
Lu Gan, Ying Liu, Dixin Cui, Yue Pan, Liwei Zheng, Mian Wan   +5 more
doaj   +1 more source

A Sequential Framework for Detection and Classification of Abnormal Teeth in Panoramic X-rays [PDF]

arXiv, 2023
This paper describes our solution for the Dental Enumeration and Diagnosis on Panoramic X-rays Challenge at MICCAI 2023. Our approach consists of a multi-step framework tailored to the task of detecting and classifying abnormal teeth. The solution includes three sequential stages: dental instance detection, healthy instance filtering, and abnormal ...
arxiv  

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Activation of the pattern recognition receptor NOD1 in periodontitis impairs the osteogenic capacity of human periodontal ligament stem cells via p38/MAPK signalling

Cell Proliferation, Volume 55, Issue 12, December 2022., 2022
Nucleotide oligomerization domain receptor 1 (NOD1) is substantially expressed in periodontium of individuals with chronic periodontitis. Abnormal activation of NOD1 may result in alveolar bone loss by impairing the osteogenic potential of human periodontal ligament stem cells, which provides a potential target in periodontium regeneration.
Yuying He, Zuping Wu, Sirui Chen, Jiahe Wang, Li Zhu, Jing Xie, Chenchen Zhou, Shujuan Zou   +7 more
wiley   +1 more source

Nanofibrous Spongy Microspheres for the Delivery of Hypoxia-primed Human Dental Pulp Stem Cells to Regenerate Vascularized Dental Pulp [PDF]

, 2016
Dental pulp infection and necrosis are widespread diseases. Conventional endodontic treatments result in a devitalized and weakened tooth. In this work, we synthesized novel star-shaped polymer to self-assemble into unique nanofibrous spongy microspheres
Hu, Jiang, Jin, Xiaobing, Kuang, Rong, Ma, Peter X., Ni, Longxing, Shi, Songtao, Zhang, Zhanpeng   +6 more
core   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

The fifth most prevalent disease is being neglected by public health organisations [PDF]

, 2018
The progress towards reduction of global mortality has produced an epidemiological transition towards non-fatal diseases, which challenge the ability of the world’s population to live in full health.
Andersson, L, Andreasen, Jo, Glendor, U, Petti, S   +3 more
core   +1 more source

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

In situ Measurement of Airborne Particle Concentration in a Real Dental Office: Implications for Disease Transmission [PDF]

arXiv, 2020
Recent guidelines by WHO recommend delaying non-essential oral health care amid COVID-19 pandemic and call for research on aerosol generated during dental procedures. Thus, this study aims to assess the mechanisms of dental aerosol dispersion in dental offices and to provide recommendations based on a quantitative study to minimize infection ...
arxiv  

Dental treatment and risk of variant CJD - a case control study [PDF]

, 2007
Objective: Knowledge of risk factors for variant CJD (vCJD) remains limited, but transmission of prion proteins via re-useable medical devices, including dental instruments, or enhanced susceptibility following trauma to the oral cavity is a concern ...
A. J. Smith, AH Lowe, AH Peden, AJ Smith, CA Llewelyn, CM Van Duijn, D. Everington, ER Mulcahy, F Blanquet-Grossard, H. J. T. Ward, HJT Ward, HJT Ward, J. Bagg, JC Bartz, K Kondo, L Ingrosso, MW Head, R. G. Will, RG Will, S Collins, S. Letters, Z Davinpour   +21 more
core   +1 more source