Results 1 to 10 of about 969,188 (200)

Endodontic flare-up incidence in pulp necrosis in Universitas Airlangga Dental Hospital (RSKGMP Universitas Airlangga)

Conservative Dentistry Journal, 2022
Background : Dental caries occurs as a result of demineralization of the hard tissues of the teeth followed by the destruction of the organic matter, resulting in bacterial invasion and death of the pulp which can lead to pulp necrosis. One of the treatments for pulp necrosis is endodontic treatment. Endodontic treatment includes root canal preparation
Galih Sampoerno, Nanik Zubaidah, Wanda Salsabilla   +2 more
core   +4 more sources

Tumor Necrosis Factor Superfamily 14 Regulates the Inflammatory Response of Human Dental Pulp Stem Cells [PDF]

Current Issues in Molecular Biology
Dental caries is a highly prevalent chronic disease that leads to dental pulp inflammation. It is treated by removing the damaged tooth structure and applying a material that promotes resolution of pulpal inflammation. Tumor necrosis factor superfamily 14 (TNFSF14) is an immunomodulatory cytokine and a member of the TNF superfamily. This study aimed to
Solaiman Al-Hadlaq, Manikandan Muthurangan   +1 more
exaly   +5 more sources

Effect of the combination of Solanesol from <i>Nicotiana tabacum</i> with calcium hydroxide on tumor necrosis factor-alpha level in human dental pulp stem cells: An <i>in vitro</i> study. [PDF]

J Conserv Dent Endod
Context: Solanesol is an active compound isolated from the leaves of Nicotiana tabacum . This compound has bioactive properties, including anti-inflammatory, antibacterial, antioxidant, and neuroprotective.
Widyastuti W, Anggraini W, Fibryanto E, Roeslan MO.   +3 more
europepmc   +3 more sources

Etiologies, risk factors and outcomes of dental pulp necrosis

International Journal Of Community Medicine And Public Health, 2021
Dental pulp necrosis is referred to the situation in which the teeth biologically die due to bacterial infection or without bacterial infection. Dental pulp necrosis can be due to a chronic progression of pulpitis, in which the tissue of soft pulp in the tooth dies due to several causes such as trauma or severe bacterial infection.
Maha Ali Abdulwahab, Musab Saeed Alqahtani, Abeer Assaf Alshammari, Suzan Essam Jiffri, Abdulrahman Mohammed Alasim, Fahad Majed Alsharidah, Naif Ibrahim Alqunfuthi, Batoul Abdulmalek Alnamnakani, Raghad Saeed Alshahrani, Norah Abdullah Alshahrani, Rian Naser Aljohani, Meshall Abdul-Lattif Almintakh   +11 more
openalex   +3 more sources

Effect of MicroRNA‐138 on Tumor Necrosis Factor‐Alpha‐Induced Suppression of Osteogenic Differentiation of Dental Pulp Stem Cells and Underlying Mechanism [PDF]

BioMed Research International, 2022
High doses of tumor necrosis factor‐α (TNF‐α) suppress osteogenic differentiation of human dental pulp stem cells (hDPSCs). In the present study, we aimed to explore the role and potential regulatory mechanism of microRNA‐138 (miR‐138) in the osteogenic differentiation of hDPSCs after treatment with a high dose of TNF‐α.
Wenzhe Liu, Kankui Wu, Wancui Wu
openalex   +3 more sources

Stimulation of EphB2/ephrin‐B1 signalling by tumour necrosis factor alpha in human dental pulp stem cells [PDF]

Cell Proliferation, 2015
AbstractObjectivesThe aim of this study was to investigate whether in vitro stimulation of dental pulp stem cells (DPSCs) by tumour necrosis factor alpha (TNF‐α) would induce secretion of EphB2/ephrin‐B1 signalling.Materials and methodsDental pulp stem cells isolated from human dental pulp were treated with TNF‐α (5–100 ng/ml) over 2–48 h. EphB2/ephrin‐
Lifang Zhu, Waruna Lakmal Dissanayaka, David W. Green, Chengfei Zhang   +3 more
openalex   +7 more sources

A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells [PDF]

Stem Cell Research & Therapy, 2014
Abstract Introduction During normal pulp tissue healing, inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α) or interleukins, act in the initial 48 hours (inflammatory phase) and play important roles not only as chemo-attractants of inflammatory cells and stem/progenitor cells but also in ...
Mayu Ueda, Takuo Fujisawa, Mitsuaki Ono, Emilio Satoshi Hara, Hai Thanh Pham, Ryu Nakajima, Wataru Sonoyama, Takuo Kuboki   +7 more
openalex   +4 more sources

Resveratrol represses tumor necrosis factor α/c-Jun N-terminal kinase signaling via autophagy in human dental pulp stem cells [PDF]

Archives of Oral Biology, 2018
To study the effects of polyphenol resveratrol on TNFα-induced inflammatory signaling as well as the underlying mechanism in human dental pulp stem cells (DPSCs).Human DPSCs were cultured and treated by TNFα in the presence or absence of resveratrol. NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways were analyzed by Western blotting ...
Fengming Wang, Zhiai Hu, Xiaohua Liu, Jian Q. Feng, Robert Augsburger, James L. Gutmann, Gerald Glickman   +6 more
openalex   +4 more sources

Effects triggered by tumor necrosis factor-α in immortalized murine dental pulp and pre-osteoblastic cells

Brazilian Oral Research
Abstract Tumor necrosis factor-alpha (TNF-α) is a cytokine involved in the immune-inflammatory response. It can induce an odontoblastic phenotype and enhance biomineralization in dental pulp mesenchymal stem cells but does not have the same effect on osteoblasts. The reasons for this differential response, despite the shared lineage of these cell types,
Giuliana de Campos Chaves Lamarque, Roberta Duarte Leme, Luciano Aparecido de Almeida‐Junior, Marília Pacífico Lucisano, Karina Fittipaldi Bombonato‐Prado, Raquel Assed Bezerra da Silva, Anne George, Francisco Wanderley Garcia Paula‐Silva   +7 more
openalex   +4 more sources

Tumor necrosis factor α stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells

Journal of Oral Science, 2012
Plasminogen activator (PA) is the enzyme responsible for converting plasminogen to its active form, plasmin, which is involved in various physiological and pathological phenomena. PA exists in two forms: urokinase-type PA (uPA) and tissue-type PA (tPA).
Takanori Narita, Koichiro Muromachi, Naoto Kamio, Sumi Nakao, Kiyoshi Matsushima, Hideki Hashizume   +5 more
openalex   +4 more sources