Results 131 to 140 of about 46,867 (155)

Hypoxia-inducible factor 1α promotes interleukin 1β and tumor necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells.

International Endodontic Journal, 2020
AIM To elucidate the role of HIF1α in pro-inflammatory cytokine mRNA expression from lipopolysaccharide (LPS)-stimulated human dental pulp cells (hDPCs).
M. Fujii, N. Kawashima, Kento Tazawa, Kentaro Hashimoto, Keisuke Nara, Sonoko Noda, Shigenori Nagai, Takashi Okiji   +7 more
semanticscholar   +1 more source

Semaphorin3A released from human dental pulp cells inhibits the increase in interleukin‐6 and CXC chemokine ligand 10 production induced by tumor necrosis factor‐α through suppression of nuclear factor‐κB activation

Cell Biology International, 2020
Human dental pulp cells (HDPCs) play an important role in pulpitis. Semaphorin3A (Sema3A), which is an axon guidance molecule, is a member of the secretory semaphorin family.
Satoru Shindo, T. Kumagai, Satomi Shirawachi, K. Takeda, H. Shiba   +4 more
semanticscholar   +1 more source

3D Graphene/silk fibroin scaffolds enhance dental pulp stem cell osteo/odontogenic differentiation.

Dental Materials, 2023
OBJECTIVES The current in vitro study aims to evaluate silk fibroin with and without the addition of graphene as a potential scaffold material for regenerative endodontics. MATERIAL AND METHODS Silk fibroin (SF), Silk fibroin/graphene oxide (SF/GO) and
S. López-García, S. Aznar-Cervantes, Ana Pagán, C. Llena, L. Forner, J. Sanz, D. García-Bernal, Sonia Sánchez-Bautista, Laura Ceballos, Victoria Fuentes, M. Melo, F. Rodríguez-Lozano, R. Oñate-Sánchez   +12 more
semanticscholar   +1 more source

Tumor Necrosis Factor Superfamily 14 Regulates the Inflammatory Response of Human Dental Pulp Stem Cells

Current Issues in Molecular Biology
Dental caries is a highly prevalent chronic disease that leads to dental pulp inflammation. It is treated by removing the damaged tooth structure and applying a material that promotes resolution of pulpal inflammation.
Abdulelah Alrshedan, Mona Elsafadi, Manikandan Muthurangan, Solaiman Al-Hadlaq   +3 more
semanticscholar   +1 more source

Biocompatibility and osteogenic potential of novel tricalcium silicate-based materials in human dental pulp stem cells: Advancing vital pulp therapies.

Dental Materials
OBJECTIVES To evaluate the cytocompatibility, bioactivity, and mineralization potential of new tricalcium silicate-based Material (Biodentine XP) on human dental pulp stem cells (hDPSCs) compared to other calcium silicate-based materials (MTA-Ang and ...
Alejandro Mora, D. García-Bernal, F. Rodríguez-Lozano, J. Ghilotti, A. Lozano, S. López-García   +5 more
semanticscholar   +1 more source

Etiology of pulp necrosis as a predictor of success in regenerative endodontics: a case report and bioinformatic analysis

Frontiers in Dental Medicine
Regenerative endodontics (RE) is a biologically based procedure designed to replace damaged dental structures, including dentin and root structures, and cells of the pulp-dentin complex. It is the first-line treatment for patients with immature permanent
Marcela Alcota, Alfredo Torres, P. Ledezma, Montserrat Mercado, P. Paredes, Fermín E. González   +5 more
semanticscholar   +1 more source

Gelatin nanofibrous scaffolds containing rutin nanoparticles: physicochemical properties, antibacterial action, and anti-inflammatory effect on dental pulp stem cells

BMC Oral Health
Bacterial infection and inflammation often are the main causes of pulp-dentin complex damage and pulp necrosis. The regeneration capacity of the pulp-dentin complex is impeded by the antibacterial and anti-inflammatory limitations of existing ...
Asiyeh Dadgar, Solmaz Maleki Dizaj, Parnian Alizadeh Oskoee, Fatemeh Pournaghi Azar, Elmira Jafari Navimipour   +4 more
semanticscholar   +1 more source

Allogeneic bone marrow mesenchymal stromal cell transplantation induces dentin pulp complex-like formation in immature teeth with pulp necrosis and apical periodontitis.

Journal of Endodontics
INTRODUCTION Dental pulp regeneration is challenging in endodontics. Cellular therapy is an alternative approach to induce dental pulp regeneration. Mesenchymal stromal cells (MSCs) have the capacity to induce dental pulp-like tissue formation.
J. Gomez-Sosa, J. Cardier, O. Wittig, Dylana Díaz-Solano, Eloisa Lara, Kharelys Duque, Giselle Ramos-González   +6 more
semanticscholar   +1 more source

Biocompatibility of Hydraulic Calcium Silicate-Based Cement MTA FlowTM on Human Dental Pulp Stem Cells In Vitro

Journal of Functional Biomaterials
Aim: hydraulic calcium silicate-based cements (HCSCs) are widely used in endodontics for vital pulp therapy and other clinical procedures due to their favorable physicochemical and biological properties.
Paulius Tušas, J. Camilleri, M. Alksnė, E. Šimoliūnas, S. Drukteinis, Eglė Marija Urbonė, V. Bukelskiene, V. Rutkūnas, V. Pečiulienė   +8 more
semanticscholar   +1 more source

Histopathological Evaluation of the Impact of Periodontitis on Dental Pulp Condition: A Systematic Literature Review.

Australian Endodontic Journal
Comprehensive treatment of periodontitis requires to assess the need of endodontic intervention. Histopathological examination is crucial to assess link between periodontitis and pulp condition.
Ana Kostenkova, Eglė Zasčiurinskienė, Greta Lodienė   +2 more
semanticscholar   +1 more source