Results 181 to 190 of about 1,148,937 (245)

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

Mechanosensitive PIEZO1 Regulates Angiogenic Signaling in Human Dental Pulp Stem Cells

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Dental pulp stem cells (DPSCs) possess multilineage differentiation potential and contribute to dental pulp regeneration through odontoblast replacement and neovascularization. Although mechanosensitive ion channels such as PIEZO1 are known to regulate stem cell fate, their role in DPSC‐mediated angiogenesis under mechanical stress remains ...
Ai Orimoto, Chihiro Nakatomi, Chiaki Kitamura, Kentaro Ono   +3 more
wiley   +1 more source

Equivalence of human and bovine dentin matrix molecules for dental pulp regeneration: proteomic analysis and biological function. [PDF]

Arch Oral Biol, 2020
Horsophonphong S, Sercia A, França CM, Tahayeri A, Reddy AP, Wilmarth PA, Surarit R, Smith AJ, Ferracane JL, Bertassoni LE.   +9 more
europepmc   +1 more source

Clinical and Radiographic Outcomes Following Unintentional Extrusion of Cold Ceramic: A Case Series of Three Patients

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In three patients with unintentional extrusion of cold ceramic beyond the root apex, favorable clinical and radiographic outcomes were observed over 2–4 years. These descriptive observations do not establish the safety or biological effects of extruded material, but support careful clinical and radiographic follow‐up when patients remain ...
Jalil Modaresi, Maaz Anwer Memon, Mojtaba Mehrabanian   +2 more
wiley   +1 more source

Photosensitive Hydrogels Encapsulating DPSCs and AgNPs for Dental Pulp Regeneration. [PDF]

Int Dent J
He Y, Zhang Y, Hu F, Chen M, Wang B, Li Y, Xu H, Dong N, Zhang C, Hu Y, Lin Z, Peng Y, Ye Q, Luo L.   +13 more
europepmc   +1 more source

Regenerative Endodontic Procedure in Mandibular First Molar: A Clinical Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Regenerative endodontic procedures (REPs) have emerged as a biologically based treatment modality for managing immature permanent teeth with necrotic pulp, offering the potential for continued root development and periapical healing. This case report describes the regenerative endodontic treatment of a necrotic, immature mandibular first molar
Sorour Saeedi, Ali Hamedi, Mani Mansouri, Iman Shiezadeh   +3 more
wiley   +1 more source

Role of Platelet Concentrates in Dental-Pulp Regeneration: A Systematic Review of Randomized Clinical Trials. [PDF]

J Dent (Shiraz)
Kiaipour Z, Shafiee M, Ansari G.
europepmc   +1 more source

Root Migration After Coronectomy of a Mandibular Third Molar With the Inferior Alveolar Nerve Passing Between the Roots: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Extraction of mandibular third molars (MTMs) is one of the most common procedures in oral and maxillofacial surgery. It carries a risk of inferior alveolar nerve (IAN) injury, which may result in altered or lost sensation of the lower lip, chin, teeth, and gingiva. Coronectomy, a surgical technique in which the crown is removed while the vital
Vito Marquez Rocco, Andreas Thor, Abdullah A. Hashim, Dominique Bellerud   +3 more
wiley   +1 more source

Long‐Term Clinical and Radiographic Outcomes of Large Periapical Lesions Managed by Non‐Surgical and Surgical Endodontic Treatment: A Case Series

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT The management of large periapical lesions is challenging, as lesion size alone does not predict treatment outcome or mandate surgery. This case series presents three large periapical lesions with 4‐ to 12‐year follow‐up, illustrating different therapeutic pathways.
Mohsen Aminsobhani, Maryam Babaahmadi, Razieh Amiri, Maryam Habibzadeh, Nazanin Kamali   +4 more
wiley   +1 more source

Tissue engineering approaches for dental pulp regeneration: The development of novel bioactive materials using pharmacological epigenetic inhibitors. [PDF]

Bioact Mater
Quigley RM, Kearney M, Kennedy OD, Duncan HF.   +3 more
europepmc   +1 more source