Results 151 to 160 of about 5,623,817 (263)

Mechanobiology of Dental Pulp Cells

The dental pulp is the inner part of the tooth responsible for properly functioning during its lifespan. Apart from the very big biological heterogeneity of dental cells, tooth microenvironments differ a lot in the context of mechanical properties ...
Andrzej Kubiak, Agnieszka Basta-Kaim, Natalia Bryniarska-Kubiak   +2 more
core   +1 more source

Functional anatomy, jaw mechanisms, and feeding behavior of Dunkleosteus terrelli (Placodermi, Arthrodira)

The Anatomical Record, Volume 309, Issue 10, Page 2574-2635, October 2026.
A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman, Robert K. Carr, Kate Trinajstic, Zerina Johanson, Oleg A. Lebedev   +4 more
wiley   +1 more source

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

International Endodontic Journal, Volume 59, Issue 10, Page 2122-2142, October 2026.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang, Jiawei Liu, Xintao Yang, Mohamad Koohi‐Moghadam, Shuting Gao, Yuanyuan Han, Dineshi Sewvandi Thalakiriyawa, James Kit Hon Tsoi, Yanqi Yang, Waruna Lakmal Dissanayaka   +9 more
wiley   +1 more source

Conhecimento dos pós-graduandos em odontologia da Universidade Federal de Santa Catarina sobre células-tronco [PDF]

, 2012
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Novas perspectivas de estudo têm ocorrido com a descoberta das células-tronco (CT), por tratar-se de células reparadoras de órgãos e tecidos lesados ...
Trajano, Juliana Martins
core  

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, Volume 59, Issue 10, Page 2028-2045, October 2026.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

Distinct Microbiota and Functional Pathway Profiles Define Success and Failure in Regenerative Endodontic Treatment

International Endodontic Journal, Volume 59, Issue 10, Page 2223-2237, October 2026.
ABSTRACT Aim To characterize the intracanal microbiota and identify key microbial taxa and functional pathways associated with regenerative endodontic treatment (RET) outcomes. Methodology In this observational cohort study, 196 samples were collected at five time points from external tooth surfaces (T1, T4) and root canals (T2, T3, T5).
Leimarembi Devi Naorem, Alina Wikström, Peter Quach, Lokeshwaran Manoharan, Ronald Ordinola‐Zapata, Olena Rakhimova, Malin Brundin, Nelly Romani Vestman   +7 more
wiley   +1 more source

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

Advanced Materials Interfaces, Volume 13, Issue 17, 8 September 2026.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung, Zizhao Li, Sung‐Han Jo, Se‐Hwan Lee, Il Keun Kwon, Jina Ko, Su Chin Heo   +6 more
wiley   +1 more source

Inhibition of METTL14 Alleviates OGD/R‐Induced Neuronal Differentiation Injury in Neural Stem Cells Through Suppressing the Tp53inp2/Ptgs2 Axis: Potential Benefits for the Mouse MCAO Model

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The graphical abstract highlights that ischemic stroke leads to increased METTL14 expression, which enhances Tp53inp2 mRNA stability through m6A modification. Elevated Tp53inp2 then promotes damaging mitophagy and ROS production by upregulating Ptgs2, ultimately impairing the neuronal differentiation of neural stem cells.
Dan Hou, Yujie Hu, Tian Yun, Dan Yu, Guoshuai Yang   +4 more
wiley   +1 more source

Exosomal PSMD1 Derived From Dental Pulp Mesenchymal Stem Cells Promotes Microglial M2 Polarization to Alleviate Spinal Cord Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
DPMSCs‐derived exosomal PSMD1 stimulates M2 polarization through the JAK2/STAT3 pathway. DPMSCs‐derived exosomal PSMD1 indirectly acts on NE‐4C cells. DPMSCs‐derived exosomal PSMD1 ameliorates SCI in a mouse model. ABSTRACT Background Exosomes derived from mesenchymal stem cells (MSCs) and their cargo contribute to the protective properties of MSCs in ...
Xiaohui Xing, Yuan Hao, Guanghui Zhang, Xiaoyang Xing, Hongfei Jia, Chenlong Liu, Xin Wang, Tao Li, Xueyuan Li, Yilei Xiao   +9 more
wiley   +1 more source

Optogenetic control of odontoblastic differentiation in dental pulp stem cells (DPSC). [PDF]

J Dent Sci
Torelli F.
europepmc   +1 more source