Results 191 to 200 of about 40,015 (316)

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 2, Page 379-392, January 2026.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha   +7 more
wiley   +1 more source

Nanostructured Scaffold, Combined with Human Dental Pulp Stem Cell Secretome, Induces Vascularization in Medicinal Leech Model [PDF]

open access: gold
Gaia Marcolli   +8 more
openalex   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

open access: yesCell Proliferation, Volume 59, Issue 1, January 2026.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng   +4 more
wiley   +1 more source

Resveratrol delays senescence of human dental pulp stem cells via activating the SIRT1-mitochondrial autophagy. [PDF]

open access: yesSci Rep
Li Z   +10 more
europepmc   +1 more source

Yerba Mate (Ilex paraguariensis A. St.‐Hil.) Reduces Oxidative Stress and Bone Resorption in Apical Periodontitis

open access: yesInternational Endodontic Journal, Volume 59, Issue 1, Page 91-104, January 2026.
ABSTRACT Aim Apical periodontitis (AP) is a highly prevalent chronic inflammatory disease that can exert systemic effects by releasing biochemical mediators that initiate and regulate the immune response. Yerba Mate (Ilex paraguariensis, YM), a popular plant broadly consumed in South America, is rich in biologically active compounds known for their ...
Carolina Sayuri Wajima   +9 more
wiley   +1 more source

The Role of Abnormal Mitochondrial Fusion and Fission in the Inflammatory Senescence of Dental Pulp Stem Cells. [PDF]

open access: yesInt Dent J
Tang W   +9 more
europepmc   +1 more source

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