Results 71 to 80 of about 1,458,616 (285)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Graphene oxide-reinforced resin composites: A novel approach to next-generation dental materials

open access: yesNext Materials
Graphene oxide (GO) has gained significant momentum in dental research for its outstanding mechanical strength, biocompatibility, and antibacterial activity.
Aliza Anwaar   +5 more
doaj   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang   +17 more
wiley   +1 more source

Biocompatibility of composite resins

open access: yesDental Research Journal, 2011
Dental materials that are used in dentistry should be harmless to oral tissues, so they should not contain any leachable toxic and diffusible substances that can cause some side effects.
Sayed Mostafa Mousavinasab
doaj   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

open access: yesAdvanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng   +15 more
wiley   +1 more source

Enhancing the performance of dental composites with nanomaterial reinforcements via stereolithographic additive manufacturing

open access: yesDiscover Nano
Aim This study investigates the enhancement of mechanical and morphological properties of dental resin composites through the incorporation of hexagonal boron nitride (hBN) and boron nitride nanotubes (BNNTs) using additive manufacturing techniques ...
Mitesh Patadia   +4 more
doaj   +1 more source

Factors influencing color match of monochromatic resin composites: a narrative review

open access: yesFrontiers in Dental Medicine
Monochromatic resin composite, a novel dental restorative material, is now increasingly utilized in dental restorations, especially for anterior teeth. Its benefits include appealing aesthetics and ease of handling.
Weibo Huang
doaj   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

Fracture Toughness of Resin Composites under Different Modes and Media: Review of Articles

open access: yesJournal of Dental Biomaterial, 2015
This article aims to review various modes of fracture toughness of resin composites. Also, this study intends to review the papers on the fracture mode, namely “fractography”, under scanning electron microscopy finding fracture initiation site, and ...
Fani M, Farmani S, Bagheri R
doaj  

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