Results 91 to 100 of about 23,915,363 (231)

Emergence of new genotypes and lineages of dengue viruses during the 2012–15 epidemics in southern India

open access: yesInternational Journal of Infectious Diseases, 2019
Objectives: To genotypically characterize dengue virus (DENV) isolates among dengue-infected children from 2012–13/2014–15 outbreaks in southern India.
Syed Fazil Ahamed   +7 more
doaj   +1 more source

Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates

open access: yesNature, 2023
JNJ-1802—a highly potent dengue virus inhibitor—blocks the NS3–NS4B interaction within the viral replication complex, and is highly effective against viral infection with DENV-1 or DENV-2 in non-human primates.
Olivia Goethals   +43 more
semanticscholar   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki   +3 more
wiley   +1 more source

TIM-1 Ubiquitination Mediates Dengue Virus Entry

open access: yesCell Reports, 2018
Summary: Dengue virus (DENV) is a major human pathogen causing millions of infections yearly. Despite intensive investigations, a DENV receptor that directly participates in virus internalization has not yet been characterized.
Ophélie Dejarnac   +16 more
doaj   +1 more source

Dengue virus neutralizing antibody levels associated with protection from infection in thai cluster studies. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
Long-term homologous and temporary heterologous protection from dengue virus (DENV) infection may be mediated by neutralizing antibodies. However, neutralizing antibody titers (NTs) have not been clearly associated with protection from infection.Data ...
Darunee Buddhari   +13 more
doaj   +1 more source

In Silico Comparative Analysis of Predicted B Cell Epitopes against Dengue Virus (Serotypes 1–4) Isolated from the Philippines

open access: yesVaccines, 2022
Dengue is a viral mosquito-borne disease that rapidly spreads in tropical and subtropical countries, including the Philippines. One of its most distinguishing characteristics is the ability of the Dengue Virus (DENV) to easily surpass the innate ...
Lyn Marielle I. Abesamis   +7 more
doaj   +1 more source

Ekspresi dan Purifikasi Protein Rekombinan Non-Struktural NS1 Virus Dengue Serotipe 1 Strain Indonesia pada Pichia Pastoris [PDF]

open access: yes, 2016
Dengue infection remains a public health problem in Indonesia. In the framework of the independence of the national product, pursued research and development of raw materials that can be used for diagnostic kit and vaccine candidates.
Lestari, C. W. (Chirstina)   +3 more
core  

Human to Mosquito Transmission of Dengue Viruses [PDF]

open access: yes, 2004
The successful transmission of dengue virus from a human host to a mosquito vector requires a complex set of factors to align. It is becoming increasingly important to improve our understanding of the parameters that shape the human to mosquito component
Lauren B. Carrington, Cameron P. Simmons
core   +1 more source

Challenges on the development of a dengue vaccine: a comprehensive review of the state of the art

open access: yesJournal of General Virology, 2023
Dengue virus (DENV) is the mosquito-borne virus of greatest human health concern. There are four serotypes of DENV (1-4) that co-circulate in endemic areas.
Jessica Pintado Silva   +1 more
semanticscholar   +1 more source

GISDD: A comprehensive global integrated sequence and genotyping database platform for dengue virus, facilitating a stratified coordinated surveillance strategy

open access: yesiMetaOmics, EarlyView.
GISDD, the Global Integrated Sequence and Genotyping Database for Dengue Virus (DENV), provides an integrated online analysis platform encompassing tools such as GISDDrlearn, GISDDprimer, and GISDDref, enabling swift identification and tracing of well‐established DENV genotypes, subgenotypes, and clades, thereby facilitating a stratified global ...
Xiang Guo   +24 more
wiley   +1 more source

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