Results 101 to 110 of about 23,915,363 (231)

The Role of Heterotypic DENV-specific CD8+T Lymphocytes in an Immunocompetent Mouse Model of Secondary Dengue Virus Infection

EBioMedicine, 2017
Dengue is the most prevalent arthropod-borne viral disease worldwide and is caused by the four dengue virus serotypes (DENV-1-4). Sequential heterologous DENV infections can be associated with severe disease manifestations.
Laura B. Talarico, Juan P. Batalle, Alana B. Byrne, Jorge M. Brahamian, Adrián Ferretti, Ayelén G. García, Aldana Mauri, Carla Simonetto, Diego R. Hijano, Andrea Lawrence, Patricio L. Acosta, Mauricio T. Caballero, Yésica Paredes Rojas, Lorena I. Ibañez, Guillermina A. Melendi, Félix A. Rey, Elsa B. Damonte, Eva Harris, Fernando P. Polack   +18 more
doaj   +1 more source

Phylogeographic analysis of dengue virus serotype 1 and cosmopolitan serotype 2 in Africa

International Journal of Infectious Diseases, 2023
Objectives: The origin and spread of dengue virus (DENV) circulating in Africa remain poorly characterized, with African sequences representing
Philippe Selhorst, Sebastian Lequime, Gytis Dudas, Sam Proesmans, Pascal Lutumba, Freddy Katshongo, Kadrie Ramadan, Isabel Micalessi, Steve Ahuka-Mundeke, Veerle Vanlerberghe, Marjan Van Esbroeck, Kevin K. Ariën   +11 more
doaj   +1 more source

Dengue Virus: Epidemiology, Biology and Disease Aetiology.

Canadian Journal of Microbiology (print), 2021
Dengue is a vector-borne viral disease, caused by the Flavivirus, Dengue virus (DENV). About 400 million cases and 22000 deaths occur due to dengue throughout the world each year.
Sudipta Roy, S. Bhattacharjee
semanticscholar   +1 more source

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

Nano Select, EarlyView.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Intrahost Selection Pressures Drive Rapid Dengue Virus Microevolution in Acute Human Infections. [PDF]

, 2017
Dengue, caused by four dengue virus serotypes (DENV-1 to DENV-4), is a highly prevalent mosquito-borne viral disease in humans. Yet, selection pressures driving DENV microevolution within human hosts (intrahost) remain unknown. We employed a whole-genome
Balmaseda, Angel, Eswarappa, Meghana, Harris, Eva, Montoya, Magelda, Parameswaran, Poornima, Trivedi, Surbhi Bharat, Wang, Chunling   +6 more
core   +1 more source

Understanding antibody-dependent enhancement in dengue: Are afucosylated IgG1s a concern?

PLoS Pathogens, 2023
Dengue is a mosquito-borne infection caused by dengue virus (DENV) of the Flaviviridae family. There are four distinct serotypes, DENV-1,-2,-3,-4, which cause outbreaks globally.
Andrew Teo, Hao Dong Tan, Thomas Loy, P. Chia, C. Chua   +4 more
semanticscholar   +1 more source

“Molecular Docking and Dynamic Studies of Amide Derivatives from Cinnamic Acid with Potential Anti‐Dengue Virus Activity”

ChemistryOpen, EarlyView.
A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados, Manuel Alejandro Hernández‐Serda, Omar Joel Villegas‐Solís, Víctor Hugo Vázquez‐Valadez, Aldo Yoshio Alarcón‐López, Pablo A. Martínez‐Soriano, Jaqueline Ramos‐Sánchez, Tannya Karen Castro‐Jiménez, José Bustos‐Arriaga, Enrique Angeles   +9 more
wiley   +1 more source

Standardization of quantitative dengue virus nonstructural-1 ELISA for quantitation of dengue virus nonstructural-1 levels in human serum

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Introduction: Dengue virus (DENV) infection is a significant global public health problem, caused by four antigenically distinct serotypes of DENV, namely, DENV-1, DENV-2, DENV-3, and DENV-4.
Puneet Bhatt, Santhosha Devadiga, Muralidhar Varma, Chiranjay Mukhopadhyay   +3 more
doaj   +1 more source

Exposure to arboviral infections and risk of rheumatoid arthritis: Findings from the MyEIRA population‐based case‐control study

Rheumatology &Autoimmunity, EarlyView.
The Malaysian Epidemiological Investigation of Rheumatoid Arthritis population‐based case‐control study examined whether prior exposure to chikungunya and dengue viruses (via IgG seropositivity) is associated with rheumatoid arthritis (RA) risk, stratified by anti‐citrullinated protein antibody (ACPA) status.
Chun Lai Too, Wahinuddin Sulaiman, Nurul‐Aain Ahmad Fauzi, Siti Aisyah Abdul Ahmad, Lau Ing Soo, Heselynn Hussein, Nor‐Shuhaila Shahril, Gun Suk Chyn, Eashwary Mageswaran, Mohd‐Shahrir Mohamed Said, Lay Kim Tan, Ainon Mohd Mokhtar, Azmillah Rosman, Muhaini Othman, Osman Ali, Lars Alfredsson, Lars Klareskog, Leonid Padyukov   +17 more
wiley   +1 more source

Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue. [PDF]

J Med Virol
ABSTRACT Dengue virus (DENV) is a major arthropod‐borne pathogen, endemic in over 100 countries and posing global health challenges. While innate immune responses and viral evasion mechanisms have been extensively studied in animal models and mononuclear cells, severe dengue can affect multiple tissues, including the central nervous system (CNS ...
Castro LM, Fernandes ER, Quaresma JAS, Lancelotti CLP, Duarte MIS, Carvalho LV, Penny R, Vasconcelos PFDC, Mello ES, Sotto MN, Pagliari C.   +10 more
europepmc   +2 more sources